Evidence map›Paper›PMID 36252801›Full record

ArticleThe American journal of tropical medicine and hygiene2022

Maternal and Neonatal Outcomes Associated with Mild COVID-19 Infection in an Obstetric Cohort in Brazil.

Carolina A D Santos, Gentil G Fonseca Filho, Manoella M Alves, Erianna Y L Macedo, Monise G de A Pontes, Artemis P Paula, Carolina T R Barreto, Felipe N Zeneide, Andréia F Nery, Reginaldo A O Freitas and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Carolina A D SantosUniversity of Campinas, UNICAMP, Faculty of Medical Science, Campinas, São Paulo, Brazil.
Gentil G Fonseca FilhoFederal University of Rio Grande do Norte, Santa Cruz, Rio Grande do Norte, Brazil.
Manoella M AlvesAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Erianna Y L MacedoAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Monise G de A PontesAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Artemis P PaulaAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Carolina T R BarretoAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Felipe N ZeneideAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Andréia F NeryFederal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Reginaldo A O FreitasAnita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Lília D'Souza-LiUniversity of Campinas, UNICAMP, Faculty of Medical Science, Department of Pediatrics, Campinas, São Paulo, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous coronavirus epidemics were associated with increased maternal morbidity, mortality, and adverse obstetric outcomes. Reports for SARS-CoV-2 indicate that the obstetric population is at increased risk for severe illness, although there are still limited data on mild COVID-19 infection during pregnancy. To determine the association between mild COVID-19 infection during pregnancy, and maternal and neonatal outcomes, we performed a prospective cohort study among pregnant women with COVID-19 and a control group. Postnatal depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale. We recruited 84 pregnant women with mild COVID-19 and 88 pregnant women without COVID-19. All participants were unvaccinated. The most common acute COVID-19 symptoms were headache (82.1%), loss of smell (81%), and asthenia (77.4%). The median duration of long COVID symptoms was 60 days (interquartile range, 130). Pregnant women with a COVID-19 diagnosis were at greater risk for obstetric ultrasound abnormalities-mainly, fetal growth restriction (relative risk [RR], 12.40; 95% CI, 1.66-92.5), premature birth (RR, 2.62; 95% CI, 1.07-6.43), and postpartum depression (RR, 2.28; 95% CI, 1.24-4.21). Our results alert clinicians to the consequences of COVID-19 during pregnancy, even in mild cases, given the increased risk of ultrasound abnormalities, premature birth, long COVID symptoms, and postpartum depression. National guidelines on preventive measures and treatments should be based on scientific evidence, including attention to the impact on health and family needs during and after the COVID-19 pandemic.

Indexed as

COVID-19Depression, PostpartumInfant, Newborn, DiseasesPregnancy ComplicationsPregnancy Complications, InfectiousPremature BirthBrazilCohort StudiesCOVID-19 TestingFemaleHumansInfant, NewbornPandemicsPost-Acute COVID-19 SyndromePregnancyPregnancy Outcome

Identifiers

PMID36252801
PMCPMC9709018
OpenAlexW4306407118

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.