Evidence map›Paper›PMID 36260679›Full record

ArticleScience advances2022

RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells.

Anil Akturk, Matthew Day, Basile Tarchini

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Anil AkturkThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-5792-4840
Matthew DayThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-0422-2132
Basile TarchiniThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0003-2708-6273
Jackson Laboratory · USTufts University · US

Funding

Hair Cell Polarization and Sensory Bundle DevelopmentR01DC015242 · NIDCD · JACKSON LABORATORY · PI Basile Robin Tarchini · 2017 to 2026
$5.4M
Mechanism and Functional Significance of Polarity Reversal in Mechanosensory OrgansR01DC018304 · NIDCD · JACKSON LABORATORY · PI CULLEN, KATHLEEN E, EATOCK, RUTH ANNE · 2020 to 2024
$3.5M
NIDCD NIH HHS R01 DC015242NIDCD NIH HHS R01 DC018304
6 · The paper itself

Abstract

Inhibitory G proteins (GNAI/Gα

Indexed as

Heterotrimeric GTP-Binding ProteinsRGS ProteinsAnimalsCarrier ProteinsCell Cycle ProteinsGTPase-Activating ProteinsGTP-Binding Protein alpha Subunits, Gi-GoGuanine Nucleotide Exchange FactorsGuanosine DiphosphateMiceStereociliaCarrier ProteinsCell Cycle ProteinsDaple protein, mouseGnai1 protein, mouseGTPase-Activating ProteinsGTP-Binding Protein alpha Subunits, Gi-GoGuanine Nucleotide Exchange FactorsGuanosine DiphosphateHeterotrimeric GTP-Binding ProteinsLGN protein, mouseRGS12 protein, mouseRGS Proteins

Identifiers

PMID36260679
PMCPMC9581478
OpenAlexW4306855796

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.