ReviewInternational journal of heart failure2020
The Role of Arterial Stiffness and Central Hemodynamics in Heart Failure.
Review in International journal of heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Heart Failure with Supranormal Ejection Fraction: An Emerging High-Risk Phenotype Within the Preserved Ejection Fraction Spectrum-A Systematic Review.Journal of clinical medicine · 2026Review
- Beyond Blood Pressure: Arterial Stiffness as a Hemodynamic and Neuroadrenergic Axis Linking Hypertension, Cardiac Remodeling, and Heart Failure.Life (Basel, Switzerland) · 2026Review
- Hemodynamic effects of red blood cell transfusion in patients with hemato-oncologic diseases.Frontiers in medicine · 2026Article
- Combined aerobic and resistance exercise training restores perivascular adipose tissue function in the thoracic aorta of rats with heart failure.Clinical science (London, England : 1979) · 2025Article
- Article
- Sex and resting heart rate influence the relation between arterial stiffness and cardiac structure and function - insights from the general population.Journal of human hypertension · 2025Article
- Developing technologies to assess vascular ageing: a roadmap from VascAgeNet.Physiological measurement · 2024Review
- Arterial Stiffness and Heart Failure With Preserved Ejection Fraction.Journal of Korean medical science · 2024Review
- Heart Stiffening in Pediatric Dilated Cardiomyopathy: Causes of Severity.The journal of Tehran Heart Center · 2024Article
- Profiling the Biomechanical Responses to Workload on the Human Myocyte to Explore the Concept of Myocardial Fatigue and Reversibility: Rationale and Design of the POWER Heart Failure Study.Journal of cardiovascular translational research · 2024Article
- Update on the Use of Pulse Wave Velocity to Measure Age-Related Vascular Changes.Current hypertension reports · 2024Review
- Arterial stiffness and hypertension.Clinical hypertension · 2023Review
- The Prognostic Value of Arterial Stiffness According to Socioeconomic Status.Journal of clinical medicine · 2023Article
- Associations of Estimated Pulse Wave Velocity with Body Mass Index and Waist Circumference among General Korean Adults.Metabolites · 2023Article
- Estimated Pulse Wave Velocity in the Prediction of Clinical Outcomes in Patients Undergoing Drug-Eluting Stent Implantation.Journal of clinical medicine · 2023Article
- Rising arterial stiffness with accumulating comorbidities associates with heart failure with preserved ejection fraction.ESC heart failure · 2023Article
- The Role of the Vasculature in Heart Failure.Current heart failure reports · 2023Review
- Arterial stiffness and its associations with left ventricular diastolic function according to heart failure types.Clinical hypertension · 2023Article
- Pulsatile Hemodynamics and Coronary Artery Disease.Korean circulation journal · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whereas traditional understanding of left ventricular afterload was focused on a steady-state circulation model with continuous pressures and flow, a more realistic concept is emerging, taking the pulsatile nature of the heart and the arterial system into account. The most simple measure of pulsatility is brachial pulse pressure, representing the pulsatility fluctuating around the mean blood pressure level. Brachial pulse pressure is widely available, fundamentally associated with the development and treatment of heart failure (HF), but its analysis is often confounded in patients with established HF. The next step of analysis consists of arterial stiffness, central (rather than brachial) pressures, and of wave reflections. The latter are closely related to left ventricular late systolic afterload, ventricular remodeling, diastolic dysfunction, exercise capacity, and, in the long term, the risk of new-onset HF. Wave reflection may also evolve as a suitable therapeutic target for HF with preserved and reduced ejection fraction. A full understanding of ventricular-arterial coupling, however, requires dedicated analysis of time-resolved pressure and flow signals. This review provides a summary of current understanding of pulsatile hemodynamics in HF.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.