Evidence map›Paper›PMID 36263299›Full record

ArticleFrontiers in nutrition2022

Triglyceride to high-density lipoprotein cholesterol ratio and total cholesterol to high-density lipoprotein cholesterol ratio and risk of benign prostatic hyperplasia in Chinese male subjects.

Chen Zhu, Juan Wu, Yixian Wu, Wen Guo, Jing Lu, Wenfang Zhu, Xiaona Li, Nianzhen Xu, Qun Zhang

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chen ZhuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Juan WuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Yixian WuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Wen GuoDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Jing LuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Wenfang ZhuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Xiaona LiDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Nianzhen XuDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Qun ZhangDepartment of Health Promotion Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Lipid metabolism disorders contribute to the risk factor of prostatic hyperplasia. Lipid ratios have also attracted a lot of attention. Yet, research about the correlation of lipid ratios with prostatic hyperplasia is limited. Hence, the aim of this study was to investigate the association of lipid ratios with the risk of benign prostatic hyperplasia (BPH) in Chinese male subjects. Methods: Healthy men who underwent routine health check-ups from January 2017 to December 2019 were recruited. Twenty-four thousand nine hundred sixty-two individuals were finally enrolled in this research. Binary logistic regression analysis was performed to investigate the relationship between lipid ratios and BPH in Chinese adults. Results: After health examinations for more than 2 years, 18.46% of subjects were ascertained as incident BPH cases. Higher age, body mass index (BMI), prostate-specific antigen (PSA), triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C), triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) ratio, and lower high-density lipoprotein cholesterol (HDL-C) were significantly associated with BPH risk, while total cholesterol (TC) was not significant. When quartiles of TG/HDL-C and TC/HDL-C were analyzed in multivariable model, higher TG/HDL-C and TC/HDL-C were associated with a risk of BPH (odds ratio [OR] = 2.11; 95% confidence interval [CI]: 1.89, 2.36; Conclusions: TG/HDL-C and TC/HDL-C were associated with BPH risk, TG/HDL-C was a powerful independent risk factor for BPH in Chinese adults, and higher TG/HDL-C ratio should be valued in male subjects with normal TG and HDL-C levels.

Indexed as

benign prostatic hyperplasiadyslipidemiahigh-density lipoprotein cholesterollipid ratiostriglycerides

Identifiers

PMID36263299
PMCPMC9574369

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.