Evidence map›Paper›PMID 36265996›Full record

ArticleJACC. Clinical electrophysiology2022

The Central Brain of the Heart: The Sinoatrial Node.

Nathan Grainger, L Fernando Santana

Open access · greenAbstract readEditorialComment
In one paragraph

Article in JACC. Clinical electrophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Emerging Regulatory Mechanisms in Sinoatrial Node Automaticity.Journal of cellular and molecular medicine · 2026
    Review
  2. Review
  3. Sinus node dysfunction: current understanding and future directions.American journal of physiology. Heart and circulatory physiology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nathan GraingerDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada, USA. Electronic address: ngrainger@unr.edu.
L Fernando SantanaDepartment of Physiology and Membrane Biology, University of California-Davis, Davis, California, USA. Electronic address: lfsantana@ucdavis.edu.
University of California, Davis · USUniversity of Nevada, Reno · US

Funding

In silico Safety PharmacologyR01HL128537 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, SANTANA, LUIS F · 2016 to 2024
$5.7M
Multi-Scale Modeling of Vascular Signaling UnitsR01HL152681 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, SANTANA, LUIS F · 2020 to 2023
$2.4M
Neuronal Kv2.1 Potassium Channels as Organizers of Somatic L-Type Calcium Channel MicrodomainsR01NS114210 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DICKSON, EAMONN JAMES, SANTANA, LUIS F · 2020 to 2024
$2.3M
NHLBI NIH HHS R01 HL128537NHLBI NIH HHS R01 HL152681NINDS NIH HHS R01 NS114210
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainSinoatrial NodeAction PotentialsHumansinterstitial cellspacemakerperipheral glial cellssinoatrial nodetelocytes

Identifiers

PMID36265996
PMCPMC10031656
OpenAlexW4306649561

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.