Evidence map›Paper›PMID 36279884›Full record

SynthesisInternational journal of cancer2023

Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta-analysis.

Doris S M Chan, Rita Vieira, Leila Abar, Dagfinn Aune, Katia Balducci, Margarita Cariolou, Darren C Greenwood, Georgios Markozannes, Neesha Nanu, Nerea Becerra-Tomás and 18 more

Open access · bronzeAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  9. The Effect of Diet on Breast Cancer Recurrence: The DIANA-5 Randomized Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 12 institutions in 7 countries.

Doris S M ChanDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.ORCID 0000-0002-0198-1897
Rita VieiraDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Leila AbarDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Dagfinn AuneDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Katia BalducciDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Margarita CariolouDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Darren C GreenwoodLeeds Institute for Data Analytics, Faculty of Medicine and Health, University of Leeds, Leeds, UK.
Georgios MarkozannesDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Neesha NanuDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Nerea Becerra-TomásDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Edward L GiovannucciDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Marc J GunterNutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.
Alan A JacksonFaculty of Medicine, School of Human Development and Health, University of Southampton, Southampton, UK.
Ellen KampmanDivision of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands.
Vivien LundWorld Cancer Research Fund International, London, UK.
Kate AllenWorld Cancer Research Fund International, London, UK.
Nigel T BrocktonAmerican Institute for Cancer Research, Arlington, Virginia, USA.
Helen CrokerWorld Cancer Research Fund International, London, UK.
Daphne KatsikiotiWorld Cancer Research Fund International, London, UK.
Deirdre McGinley-GieserAmerican Institute for Cancer Research, Arlington, Virginia, USA.
Panagiota MitrouWorld Cancer Research Fund International, London, UK.
Martin WisemanWorld Cancer Research Fund International, London, UK.
Amanda J CrossDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Elio RiboliDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Steven K ClintonDivision of Medical Oncology, The Department of Internal Medicine, College of Medicine and Ohio State University Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA.
Anne McTiernanDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Teresa NoratDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Konstantinos K TsilidisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.ORCID 0000-0002-8452-8472
Imperial College London · GBWorld Cancer Research Fund International · GBAmerican Institute for Cancer Research · USUniversity of Ioannina · GRCentre international de recherche sur le cancer · FRFred Hutch Cancer Center · USHarvard University · USNational Institute for Health Research · GBOslo University Hospital · NOThe Ohio State University · USUniversity of Leeds · GBWageningen University & Research · NL

Funding

Cancer Research UK 25004World Health Organization 001
6 · The paper itself

Abstract

Previous evidence on postdiagnosis body fatness and mortality after breast cancer was graded as limited-suggestive. To evaluate the evidence on body mass index (BMI), waist circumference, waist-hip-ratio and weight change in relation to breast cancer prognosis, an updated systematic review was conducted. PubMed and Embase were searched for relevant studies published up to 31 October, 2021. Random-effects meta-analyses were conducted to estimate summary relative risks (RRs). The evidence was judged by an independent Expert Panel using pre-defined grading criteria. One randomized controlled trial and 225 observational studies were reviewed (220 publications). There was strong evidence (likelihood of causality: probable) that higher postdiagnosis BMI was associated with increased all-cause mortality (64 studies, 32 507 deaths), breast cancer-specific mortality (39 studies, 14 106 deaths) and second primary breast cancer (11 studies, 5248 events). The respective summary RRs and 95% confidence intervals per 5 kg/m

Indexed as

Breast NeoplasmsAdipose TissueBody Mass IndexFemaleHumansWaist CircumferenceWaist-Hip RatioBody fatnessbreast cancer survivalevidence gradingsystematic reviewweight change

Identifiers

PMID36279884
PMCPMC10092239
OpenAlexW4307298806

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.