Evidence map›Paper›PMID 36280223›Full record

ArticleExperimental eye research2022

Synaptotagmins 1 and 7 in vesicle release from rods of mouse retina.

C S Mesnard, C L Hays, C L Barta, A L Sladek, J J Grassmeyer, K K Hinz, R M Quadros, C B Gurumurthy, W B Thoreson

Open access · greenAbstract read
In one paragraph

Article in Experimental eye research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Article
  11. Three-Dimensional Ultrastructure of the Normal Rod Photoreceptor Synapse and Degenerative Changes Induced by Retinal Detachment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

C S MesnardTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA; Pharmacology and Experimental Neuroscience, USA.
C L HaysTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA.
C L BartaTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA.
A L SladekTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA.
J J GrassmeyerTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA; Pharmacology and Experimental Neuroscience, USA.
K K HinzTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA.
R M QuadrosPharmacology and Experimental Neuroscience, USA; Mouse Genome Engineering Core Facility, Vice Chancellor for Research Office, College of Medicine, University of Nebraska Medical Center, Omaha, NE, 68106, USA.
C B GurumurthyPharmacology and Experimental Neuroscience, USA; Mouse Genome Engineering Core Facility, Vice Chancellor for Research Office, College of Medicine, University of Nebraska Medical Center, Omaha, NE, 68106, USA.
W B ThoresonTruhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, USA; Pharmacology and Experimental Neuroscience, USA. Electronic address: wbthores@unmc.edu.
Society on Neuroimmune Pharmacology · USUniversity of Nebraska Medical Center · US

Funding

Regulation of Photoreceptor NeurotransmisssionR01EY010542 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KARATEKIN, ERDEM, THORESON, WALLACE B · 2001 to 2023
$7.7M
Development of Modular CRISPR Genome Editing Technologies and ToolsR35HG010719 · NHGRI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GURUMURTHY, CHANNABASAVAIAH · 2019 to 2023
$2.2M
Synaptic transmission at retinal ribbon synapsesR01EY032396 · NEI · YALE UNIVERSITY · PI THORESON, WALLACE B, ZENISEK, DAVID PAUL · 2021 to 2024
$1.9M
Engineering Long ssDNA for Genome Editing ApplicationsR21GM129559 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GURUMURTHY, CHANNABASAVAIAH, WHITEHEAD, TIMOTHY ANDREW · 2019 to 2020
$414k
Investigating Ca2+ dependent mechanisms of mammalian photoreceptor neurotransmissionF30EY028848 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GRASSMEYER, JUSTIN J · 2018 to 2020
$132k
CHLORIDE REGULATION OF PHOTORECEPTOR NEUROTRANSMISSIONR29EY010542 · NEI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI THORESON, WALLACE B · 1996 to 2000
$105k
NEI NIH HHS F30 EY028848NEI NIH HHS R01 EY010542NEI NIH HHS R01 EY032396NEI NIH HHS R29 EY010542NHGRI NIH HHS R35 HG010719NIGMS NIH HHS R21 GM129559
6 · The paper itself

Abstract

Synaptotagmins are the primary Ca

Indexed as

ExocytosisSynaptic TransmissionAnimalsCalciumGlutamic AcidMiceRetinaSynapsesCalciumGlutamic AcidConesElectroretinogramExocytosisMouseNeuroscienceRetinaRibbon synapseRods

Identifiers

PMID36280223
PMCPMC9830644
OpenAlexW4307153755

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.