Evidence map›Paper›PMID 36285487›Full record

ReviewCancer science2023

Phosphatase-independent role of phosphatase of regenerating liver in cancer progression.

Yosuke Funato, Osamu Hashizume, Hiroaki Miki

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. PRL-3: unveiling a new horizon in cancer therapy.Acta pharmacologica Sinica · 2025
    Review
  4. Article
  5. International journal of molecular sciences · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yosuke FunatoDepartment of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.ORCID https://orcid.org/0000-0002-4288-7717
Osamu HashizumeDepartment of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Hiroaki MikiDepartment of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
The University of Osaka · JP

Funding

Japan Science and Technology Agency JPMJFR216AJapan Society for the Promotion of Science 20H03515Japan Society for the Promotion of Science 20H05789Japan Society for the Promotion of Science 20K07312Japan Society for the Promotion of Science 21H05272Japan Society for the Promotion of Science 21K19406Japan Society for the Promotion of Science 22K06205
6 · The paper itself

Abstract

Phosphatase of regenerating liver (PRL) is a family of protein tyrosine phosphatases (PTPs) that are anchored to the plasma membrane by prenylation. They are frequently overexpressed in various types of malignant cancers and their roles in cancer progression have received considerable attention. Mutational analyses of PRLs have shown that their intrinsic phosphatase activity is dispensable for tumor formation induced by PRL overexpression in a lung metastasis model using melanoma cells. Instead, PRLs directly bind to cyclin M (CNNM) Mg

Indexed as

Caenorhabditis elegansLung NeoplasmsAnimalsCell MembraneLiverMammalsMiceProtein Tyrosine PhosphatasesProtein Tyrosine Phosphatasesacid addictioncancer progressioncyclin MMg2+phosphatase of regenerating liver

Identifiers

PMID36285487
PMCPMC9807511
OpenAlexW4307340632

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.