Evidence mapPaperPMID 36289874Full record

ReviewBiomedicines2022

The Sexual Dimorphism of Human Adipose Depots.

Nathalie Boulet, Anais Briot, Jean Galitzky, Anne Bouloumié

Abstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Obesity: a gender-view.Journal of endocrinological investigation · 2024
    Review
  13. The impact of chromosomal sex on cardiometabolic health and disease.Trends in endocrinology and metabolism: TEM · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nathalie BouletInserm, Unité Mixte de Recherche (UMR) 1297, Team 1, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université de Toulouse, F-31432 Toulouse, France.ORCID 0000-0003-1011-3474
Anais BriotInserm, Unité Mixte de Recherche (UMR) 1297, Team 1, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université de Toulouse, F-31432 Toulouse, France.
Jean GalitzkyInserm, Unité Mixte de Recherche (UMR) 1297, Team 1, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université de Toulouse, F-31432 Toulouse, France.ORCID 0000-0001-6905-3547
Anne BouloumiéInserm, Unité Mixte de Recherche (UMR) 1297, Team 1, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université de Toulouse, F-31432 Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The amount and the distribution of body fat exhibit trajectories that are sex- and human species-specific and both are determinants for health. The enhanced accumulation of fat in the truncal part of the body as a risk factor for cardiovascular and metabolic diseases is well supported by epidemiological studies. In addition, a possible independent protective role of the gluteofemoral fat compartment and of the brown adipose tissue is emerging. The present narrative review summarizes the current knowledge on sexual dimorphism in fat depot amount and repartition and consequences on cardiometabolic and reproductive health. The drivers of the sex differences and fat depot repartition, considered to be the results of complex interactions between sex determination pathways determined by the sex chromosome composition, genetic variability, sex hormones and the environment, are discussed. Finally, the inter- and intra-depot heterogeneity in adipocytes and progenitors, emphasized recently by unbiased large-scale approaches, is highlighted.

Indexed as

brown adipose tissuegluteofemoralobesity

Identifiers

PMID36289874
PMCPMC9599294

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.