Evidence map›Paper›PMID 36289944›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Synthetic Amphipathic β-Sheet Temporin-Derived Peptide with Dual Antibacterial and Anti-Inflammatory Activities.

Rosa Bellavita, Elisabetta Buommino, Bruno Casciaro, Francesco Merlino, Floriana Cappiello, Noemi Marigliano, Anella Saviano, Francesco Maione, Rosaria Santangelo, Maria Luisa Mangoni and 3 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Anandamide Targets Membrane Integrity in Non-Journal of fungi (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Temporins: Multifunctional Peptides from Frog Skin.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rosa BellavitaDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-2163-5163
Elisabetta BuomminoDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-9955-3179
Bruno CasciaroLaboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1295-1084
Francesco MerlinoDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-9607-229X
Floriana CappielloLaboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3423-8474
Noemi MariglianoDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.
Anella SavianoDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.
Francesco MaioneDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-2280-4299
Rosaria SantangeloAlsa Lab SAS., Consorzio Fracta Labor Area PIP Lotto 25, Frattamaggiore, 80027 Naples, Italy.
Maria Luisa MangoniLaboratory Affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5991-5868
Stefania GaldieroDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-7849-7024
Paolo GriecoDepartment of Pharmacy, University of Naples "Federico II", Via Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-6854-8123
Annarita FalangaDepartment of Agricultural Science, University of Naples "Federico II", 80055 Portici, Italy.ORCID 0000-0001-6538-8585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporin family is one of the largest among antimicrobial peptides (AMPs), which act mainly by penetrating and disrupting the bacterial membranes. To further understand the relationship between the physical-chemical properties and their antimicrobial activity and selectivity, an analogue of Temporin L, [Nle

Indexed as

anti-inflammatory activityantimicrobial peptidespeptide hydrophobicityphysical-chemical propertyTemporin L

Identifiers

PMID36289944
PMCPMC9598925

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.