ArticleAnimals : an open access journal from MDPI2022
Influence of Bile Salts and Pancreatin on Dog Food during Static In Vitro Simulation to Mimic In Vivo Digestion.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- In-vitro metabolite identification for MEDI7219, an oral GLP-1 analog, using LC-MS/MS with CID and EAD approaches.Bioanalysis · 2025Article
- Prediction of apparent total tract digestion of crude protein in adult dogs.Journal of animal science and technology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The addition of pancreatin and bile salts in different concentrations during in vitro digestion causes changes in the digestibility of crude protein (CP), fat, and dry matter (DM). The effects of bile salts and pancreatin on the digestibility of ether extract (EE), CP, and DM in developing a static in vitro digestion model for dogs were assessed using different concentrations of pancreatin (0, 1, 2.5, 5, and 10 g/L digestive solution) and bile salts (0, 2.5, 6.25, 12.5, and 25 g/L digestive solution). The data were analyzed using one-way analysis of variance. Digestibility of EE increased with the addition of bile salts (p < 0.05), whereas that of CP decreased with ≤0.25 g (1.0 g/L digestive solution) pancreatin. The digestibility of DM decreased significantly in all groups supplemented with ≥3.125 g (12.5 g/L digestive solution) bile salts and 0.25−2.5 g (1−10 g/L digestive solution) pancreatin and was the lowest with 6.25 g (25 g/L digestive solution) of bile salts (p < 0.05). These findings could facilitate the development of effective static in vitro digestion models for dogs.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.