Evidence map›Paper›PMID 36290231›Full record

ArticleAnimals : an open access journal from MDPI2022

Genomic Tools for the Characterization of Local Animal Genetic Resources: Application in

Marco Tolone, Maria Teresa Sardina, Gabriele Senczuk, Giorgio Chessari, Andrea Criscione, Angelo Moscarelli, Silvia Riggio, Ilaria Rizzuto, Rosalia Di Gerlando, Baldassare Portolano and 1 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat.Animals : an open access journal from MDPI · 2024
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Marco ToloneDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-6043-9782
Maria Teresa SardinaDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0001-9527-6197
Gabriele SenczukDipartimento di Agricoltura, Ambiente e Alimenti, University of Molise, 86100 Campobasso, Italy.ORCID 0000-0001-8889-2290
Giorgio ChessariDipartimento Agricoltura, Alimentazione e Ambiente, University of Catania, 95131 Catania, Italy.ORCID 0000-0002-9841-4820
Andrea CriscioneDipartimento Agricoltura, Alimentazione e Ambiente, University of Catania, 95131 Catania, Italy.ORCID 0000-0002-6701-1906
Angelo MoscarelliDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.
Silvia RiggioDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.
Ilaria RizzutoDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.
Rosalia Di GerlandoDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0001-5135-6531
Baldassare PortolanoDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.
Salvatore MastrangeloDipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0001-6511-1981
University of Palermo · ITUniversity of Catania · ITUniversity of Molise · IT

Funding

Co.Ri.A.L, Conservazione Risorse Animali Locali IRIS PRJ-0717, CUP G72C21000580009
6 · The paper itself

Abstract

Italy contains a large number of local goat populations, some of which do not have a recognized genetic structure. The "Mascaruna" is a goat population reared for milk production in Sicily. In this study, a total of 72 individuals were genotyped with the Illumina Goat_IGGC_65K_v2 BeadChip with the aim to characterize the genetic diversity, population structure and relatedness with another 31 Italian goat populations. The results displayed a moderate level of genetic variability for Mascaruna, in concordance with the estimated values for Italian goats. Runs of homozygosity islands are linked to genes involved in milk production, immune response and local adaptation. Population structure analyses separated Mascaruna from the other goat populations, indicating a clear genetic differentiation. Although they are not conclusive, our current results represent a starting point for the creation of monitoring and conservation plans. Additional analyses and a wider sampling would contribute to refine and validate these results. Finally, our study describing the diversity and structure of Mascaruna confirms the usefulness of applied genomic analyses as valid tools for the study of the local uncharacterized genetic resources.

Indexed as

genetic structurelocal goatsingle nucleotide polymorphisms

Identifiers

PMID36290231
PMCPMC9597745
OpenAlexW4306839691

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.