Evidence map›Paper›PMID 36290640›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Design and Synthesis of (

Jeongin Ko, Jieun Lee, Hee Jin Jung, Sultan Ullah, Yeongmu Jeong, Sojeong Hong, Min Kyung Kang, Yu Jung Park, YeJi Hwang, Dongwan Kang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Design, synthesis, andRSC advances · 2024
    Article
  3. Exploration of Compounds with 2-Phenylbenzo[Molecules (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. Design and Synthesis of (Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Jeongin KoDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Jieun LeeDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Hee Jin JungDepartment of Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.ORCID 0000-0001-7212-5572
Sultan UllahDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, FL 33458, USA.
Yeongmu JeongDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Sojeong HongDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Min Kyung KangDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Yu Jung ParkDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
YeJi HwangDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.
Dongwan KangNew Drug Development Center, Department of Medicinal Chemistry, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea.
Yujin ParkNew Drug Development Center, Department of Medicinal Chemistry, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea.
Pusoon ChunCollege of Pharmacy and Inje Institute of Pharmaceutical Sciences and Research, Inje University, Gimhae 50834, Korea.
Jin-Wook YooDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.ORCID 0000-0001-5216-5518
Hae Young ChungDepartment of Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.ORCID 0000-0002-3215-8828
Hyung Ryong MoonDepartment of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea.ORCID 0000-0003-1119-7112
Pusan National University · KRDaegu-Gyeongbuk Medical Innovation Foundation · KRInje University · KRScripps Research Institute · US

Funding

2-Year Research Grant from Pusan National University 2-Year Research Grant from Pusan National University
6 · The paper itself

Abstract

Many compounds containing the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, including cinnamamide derivatives, have been shown to inhibit tyrosinase potently in vitro and in vivo. Structural changes to cinnamamide derivatives were produced by adding a dithionate functional group to provide eight (

Indexed as

anti-melanogenesisantioxidantdockingPUSC scaffoldrhodaninetyrosinase

Identifiers

PMID36290640
PMCPMC9598926
OpenAlexW4297268593

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.