Evidence mapPaperPMID 36290676Full record

ArticleAntioxidants (Basel, Switzerland)2022

Onion and Apple Functional Ingredients Intake Improves Antioxidant and Inflammatory Status and Vascular Injury in Obese Zucker Rats.

Claudia Balderas, Javier Angulo, Alejandro Sevilleja-Ortiz, Concepción Peiró, Susana Vallejo, Pilar Dongil, Begoña de Ancos, Concepción Sánchez-Moreno

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Claudia BalderasInstitute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), ES-28040 Madrid, Spain.ORCID 0000-0002-8524-0219
Javier AnguloRamón y Cajal Institute for Health Research (IRYCIS), ES-28034 Madrid, Spain.ORCID 0000-0002-3789-9465
Alejandro Sevilleja-OrtizRamón y Cajal Institute for Health Research (IRYCIS), ES-28034 Madrid, Spain.ORCID 0000-0002-8521-2058
Concepción PeiróPharmacology Department, Faculty of Medicine, Universidad Autónoma de Madrid (UAM), ES-28029 Madrid, Spain.ORCID 0000-0002-9690-7816
Susana VallejoPharmacology Department, Faculty of Medicine, Universidad Autónoma de Madrid (UAM), ES-28029 Madrid, Spain.
Pilar DongilPharmacology Department, Faculty of Medicine, Universidad Autónoma de Madrid (UAM), ES-28029 Madrid, Spain.
Begoña de AncosInstitute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), ES-28040 Madrid, Spain.ORCID 0000-0002-8890-7525
Concepción Sánchez-MorenoInstitute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), ES-28040 Madrid, Spain.ORCID 0000-0002-2341-9328
Consejo Superior de Investigaciones Científicas · ESUniversidad Autónoma de Madrid · ESInstituto Cajal · ES

Funding

MCIN/AEI/10.13039/501100011033 and "ERDF A way of making Europe" AGL2016-76817-R, PID2019-107980RB-I00, PID2020-115590RB-100
6 · The paper itself

Abstract

The objective of this study was to investigate the effects of onion and apple functional ingredients in homozygous (fa/fa) obese Zucker rats. Rodents were fed three diets: standard diet [obese control (OC) group], standard diet containing 10% onion [obese onion 10% (OO) group] and standard diet containing 10% apple [obese apple 10% (OA) group] for 8 weeks. Food intake and body weight gain were higher in obese than in lean rats. Food efficiency was lower in OO and AO groups compared with OC group. Within the obese groups, total cholesterol, LDL-cholesterol, triacylglycerols, glucose, insulin and triglyceride-glucose index were lower in OO group than in OC group, and HDL-cholesterol was higher in OO group than in OC group. In general, antioxidant activity (ABTS

Indexed as

antioxidant enzymesendothelial functionfunctional foods and ingredientslipid profilemetabolic hormonesNFKβ1 and COX2 gene expressionNLRP3oxidative stressvascular injury biomarkers

Identifiers

PMID36290676
PMCPMC9598408
OpenAlexW4297973669

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.