Evidence map›Paper›PMID 36290795›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Antioral Cancer Effects by the Nitrated [6,6,6]Tricycles Compound (SK1) In Vitro.

Yan-Ning Chen, Chieh-Kai Chan, Ching-Yu Yen, Jun-Ping Shiau, Meng-Yang Chang, Cheng-Chung Wang, Jiiang-Huei Jeng, Jen-Yang Tang, Hsueh-Wei Chang

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Advances in Small Molecular Agents against Oral Cancer.Molecules (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yan-Ning ChenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chieh-Kai ChanInstitute of Chemistry, Academia Sinica, Taipei 115024, Taiwan.ORCID 0000-0002-5178-156X
Ching-Yu YenSchool of Dentistry, Taipei Medical University, Taipei 11031, Taiwan.
Jun-Ping ShiauDivision of Breast Oncology and Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Meng-Yang ChangDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-1983-8570
Cheng-Chung WangInstitute of Chemistry, Academia Sinica, Taipei 115024, Taiwan.ORCID 0000-0003-2629-4011
Jiiang-Huei JengSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Jen-Yang TangDepartment of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.ORCID 0000-0002-5690-0708
Hsueh-Wei ChangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0003-0068-2366
Kaohsiung Medical University · TWInstitute of Chemistry, Academia Sinica · TWChi Mei Medical Center · TW

Funding

Kaohsiung Medical University KMU-DK(A)111008Kaohsiung Medical University Research Center KMU-TC108A04Ministry of Science and Technology MOST 111-2320-B-037-015-MY3; MOST 110-2314-B-037-074-MY3
6 · The paper itself

Abstract

A novel nitrated [6,6,6]tricycles-derived compound containing nitro, methoxy, and ispropyloxy groups, namely SK1, was developed in our previous report. However, the anticancer effects of SK1 were not assessed. Moreover, SK1 contains two nitro groups (NO

Indexed as

apoptosisDNA damagenitrated [6,6,6]tricyclesoral cancer cellsoxidative stress

Identifiers

PMID36290795
PMCPMC9598307
OpenAlexW4306921239

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.