Evidence map›Paper›PMID 36290847›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

A Regional Survey on Merkel Cell Carcinoma: A Plea for Uniform Patient Journey Modeling and Diagnostic-Therapeutic Pathway.

Michela Roberto, Andrea Botticelli, Alessio Caggiati, Alberto Chiriatti, Carlo Della Rocca, Virginia Ferraresi, Felice Musicco, Giovanni Pellacani, Paolo Marchetti

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Michela RobertoMedical Oncology Unit A, Umberto I University Hospital, Sapienza University, 00100 Rome, Italy.ORCID 0000-0001-5339-8348
Andrea BotticelliDepartment of Radiological, Oncological and Anatomopathological Science, Umberto I University Hospital, 00161 Rome, Italy.
Alessio CaggiatiIstituto Dermopatico dell'Immacolata IRCCS, 00167 Rome, Italy.
Alberto ChiriattiPrimary Care Physician Azienda Sanitaria Locale (ASL) Roma 3, 00125 Rome, Italy.
Carlo Della RoccaDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University, Pathology Service, Umberto I University Hospital, 00185 Rome, Italy.
Virginia FerraresiSarcomas and Rare Tumors Departmental Unit, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Felice MusiccoIRCCS IFO Regina Elena and San Gallicano Institute, 00144 Rome, Italy.
Giovanni PellacaniDermatology Clinic, Department of Clinical, Internal, Anesthesiological and Cardiovascular Science, University of Rome, 00185 La Sapienza, Italy.
Paolo MarchettiDepartment of Radiological, Oncological and Anatomopathological Science, Umberto I University Hospital, 00161 Rome, Italy.ORCID 0000-0002-9064-8761
Policlinico Umberto I · ITASL Roma · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Dermopatico dell'Immacolata · ITSan Gallicano Hospital · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neuroendocrine cancer that usually affects the elderly and immunosuppressed in sun-exposed areas. Due to its rarity, it is frequently unrecognized, and its management is not standardized across medical centers, despite the more recent availability of immunotherapy, with avelumab as first-line treatment improving the prognosis even in advanced stages of disease. We conducted a purpose-designed survey of a selected sample of physicians working in the Lazio region, in Italy, to assess their awareness and knowledge of MCC as well as their perspective on assisted diagnostic and therapeutic pathways. The Lazio region, and in particular Rome, is one of the most important academic and non- academic center in Italy dedicated to the diagnosis and treatment of skin cancer. A total of 368 doctors (including 100 general practitioners, 72 oncologists, 87 dermatologists, 59 surgeons, and 50 anatomopathologists) agreed to be part of this survey. Surgeons, oncologists, and dermatologists thought themselves significantly more updated on MCC than primary care physicians, but more than half of the interviewees are interested in CCM training courses and training with clearer and more standardized care pathways. Significant differences have been reported from survey participants in terms of multidisciplinary team set up for MCC management. The identification of specialized centers and the improvement of communication pathways among different specialties, as well as between patients and physicians, could be very beneficial in improving patients' journey modeling and starting a uniform diagnostic and therapeutic pathway for MCC patients in the new era of immunotherapies.

Indexed as

Carcinoma, Merkel CellSkin NeoplasmsAgedCombined Modality TherapyHumansImmunotherapyPrognosisavelumabdiagnostic and therapeutic pathwayMerkel cell carcinoma (MCC)multidisciplinary team (MDT)survey

Identifiers

PMID36290847
PMCPMC9600681
OpenAlexW4303629052

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.