Evidence mapPaperPMID 36293182Full record

ReviewInternational journal of molecular sciences2022

Role of Micronutrients and Gut Microbiota-Derived Metabolites in COVID-19 Recovery.

Teresita de Jesús Hernández-Flores, Eliza Julia Pedraza-Brindis, Jhonathan Cárdenas-Bedoya, José Daniel Ruíz-Carrillo, Anibal Samael Méndez-Clemente, Marco Alonso Martínez-Guzmán, Liliana Iñiguez-Gutiérrez

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Comparative urinary metabolomics reveals unique and shared pathways in COVID-19 and liver diseases.Metabolomics : Official journal of the Metabolomic Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Teresita de Jesús Hernández-FloresDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-2849-8635
Eliza Julia Pedraza-BrindisDepartamento de Aparatos y Sistemas I, Facultad de Medicina, Universidad Autónoma de Guadalajara, Guadalajara 44670, Jalisco, Mexico.ORCID 0000-0002-4534-1736
Jhonathan Cárdenas-BedoyaDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.
José Daniel Ruíz-CarrilloClínica Medicina Familiar 1 del ISSSTE "Dr. Arturo González Guzmán", Guadalajara 44340, Jalisco, Mexico.
Anibal Samael Méndez-ClementeInstituto de Investigación de Inmunodeficiencias y VIH, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.ORCID 0000-0001-8120-896X
Marco Alonso Martínez-GuzmánDepartamento de Aparatos y Sistemas I, Facultad de Medicina, Universidad Autónoma de Guadalajara, Guadalajara 44670, Jalisco, Mexico.
Liliana Iñiguez-GutiérrezInstituto de Investigación de Inmunodeficiencias y VIH, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
Universidad Autónoma de Guadalajara · MXHospital Civil de Guadalajara · MXInstitute for Social Security and Services for State Workers · MXMexican Social Security Institute · MXUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A balanced and varied diet provides diverse beneficial effects on health, such as adequate micronutrient availability and a gut microbiome in homeostasis. Besides their participation in biochemical processes as cofactors and coenzymes, vitamins and minerals have an immunoregulatory function; meanwhile, gut microbiota and its metabolites coordinate directly and indirectly the cell response through the interaction with the host receptors. Malnourishment is a crucial risk factor for several pathologies, and its involvement during the Coronavirus Disease 2019 pandemic has been reported. This pandemic has caused a significant decline in the worldwide population, especially those with chronic diseases, reduced physical activity, and elder age. Diet and gut microbiota composition are probable causes for this susceptibility, and its supplementation can play a role in reestablishing microbial homeostasis and improving immunity response against Coronavirus Disease 2019 infection and recovery. This study reviews the role of micronutrients and microbiomes in the risk of infection, the severity of disease, and the Coronavirus Disease 2019 sequelae.

Indexed as

COVID-19Gastrointestinal MicrobiomeAgedCoenzymesHumansMicronutrientsVitaminsCoenzymesMicronutrientsVitaminsCOVID-19COVID-19 recoverygut microbiotamicrobiota-derived metabolitesmicronutrientsSARS-CoV-2

Identifiers

PMID36293182
PMCPMC9604189
OpenAlexW4306385422

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.