Evidence map›Paper›PMID 36293309›Full record

ArticleInternational journal of molecular sciences2022

The Corticosterone-Glucocorticoid Receptor-AP1/CREB Axis Inhibits the Luteinizing Hormone Receptor Expression in Mouse Granulosa Cells.

Xuan Zhang, Yinghui Wei, Xiaoxuan Li, Chengyu Li, Liangliang Zhang, Zhaojun Liu, Yan Cao, Weijian Li, Xiying Zhang, Jiaqing Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xuan ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yinghui WeiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xiaoxuan LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Chengyu LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Liangliang ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Zhaojun LiuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yan CaoCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Weijian LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Xiying ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jiaqing ZhangInstitute of Animal Husbandry and Veterinary Science, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China.
Ming ShenCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-1219-225X
Honglin LiuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Nanjing Agricultural University · CNHenan Academy of Agricultural Sciences · CN

Funding

Fundamental Research Funds for the Central Universities KJQN201705National Natural Science Foundation of China 31601939National Natural Science Foundation of China 31630072National Natural Science Foundation of China 31972564National Natural Science Foundation of China 31972571Natural Science Foundation of Jiangsu Province BK20221512Program for the Top Young Talents in College of Animal Science and Technology at Nanjing Agricultural University DKQB201903
6 · The paper itself

Abstract

Under stress conditions, luteinizing hormone (LH)-mediated ovulation is inhibited, resulting in insufficient oocyte production and excretion during follicular development. When the body is stressed, a large amount of corticosterone (CORT) is generated, which will lead to a disorder of the body's endocrine system and damage to the body. Our previous work showed that CORT can block follicular development in mice. Since LH acts through binding with the luteinizing hormone receptor (

Indexed as

CorticosteroneReceptors, LHAnimalsDimethyl SulfoxideFemaleGlucocorticoidsGonadotropins, EquineGranulosa CellsHorsesLuteinizing HormoneMiceMice, Inbred ICRReceptors, GlucocorticoidReceptors, G-Protein-CoupledTranscription FactorsCorticosteroneDimethyl SulfoxideGlucocorticoidsGonadotropins, EquineLuteinizing HormoneReceptors, GlucocorticoidReceptors, G-Protein-CoupledReceptors, LHTranscription Factorscorticosteroneglucocorticoid receptorgranulosa cellsluteinizing hormone receptor

Identifiers

PMID36293309
PMCPMC9604301
OpenAlexW4306742822

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.