Evidence map›Paper›PMID 36293452›Full record

ArticleInternational journal of molecular sciences2022

Computational Modeling and Imaging of the Intracellular Oxygen Gradient.

Andrew J H Sedlack, Rozhin Penjweini, Katie A Link, Alexandra Brown, Jeonghan Kim, Sung-Jun Park, Jay H Chung, Nicole Y Morgan, Jay R Knutson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Andrew J H SedlackBiomedical Engineering and Physical Science Shared Resource, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892-5766, USA.ORCID 0000-0003-0139-952X
Rozhin PenjweiniLaboratory of Advanced Microscopy and Biophotonics, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.
Katie A LinkLaboratory of Advanced Microscopy and Biophotonics, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.ORCID 0000-0001-7140-2005
Alexandra BrownLaboratory of Obesity and Aging Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.
Jeonghan KimLaboratory of Obesity and Aging Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.ORCID 0000-0003-1695-9630
Sung-Jun ParkLaboratory of Obesity and Aging Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.
Jay H ChungLaboratory of Obesity and Aging Research, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.
Nicole Y MorganBiomedical Engineering and Physical Science Shared Resource, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892-5766, USA.
Jay R KnutsonLaboratory of Advanced Microscopy and Biophotonics, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD 20892-1412, USA.
National Institutes of Health · US

Funding

National Institute of Health NHLBI
6 · The paper itself

Abstract

Computational modeling can provide a mechanistic and quantitative framework for describing intracellular spatial heterogeneity of solutes such as oxygen partial pressure (pO

Indexed as

OxygenOxygen ConsumptionComputer SimulationEnergy MetabolismHumansMyoglobinMyoglobinOxygenfinite-element analysismitochondrial pO2 gradientmyoglobin-mCherry

Identifiers

PMID36293452
PMCPMC9604273
OpenAlexW4306920801

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.