Evidence map›Paper›PMID 36294429›Full record

ReviewJournal of clinical medicine2022

Challenges in the Management of the Patient with a Failing Kidney Graft: A Narrative Review.

Rita Leal, Clara Pardinhas, António Martinho, Helena Oliveira Sá, Arnaldo Figueiredo, Rui Alves

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rita LealNephrology Department, Centro Hospitalar e Universitário de Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0614-3902
Clara PardinhasNephrology Department, Centro Hospitalar e Universitário de Coimbra, 3000-548 Coimbra, Portugal.
António MartinhoCoimbra Histocompatibility Center, Portuguese Institute of Blood and Transplantation, 3041-861 Coimbra, Portugal.
Helena Oliveira SáNephrology Department, Centro Hospitalar e Universitário de Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-5231-2629
Arnaldo FigueiredoFaculty of Medicine, University of Coimbra, 3004-531 Coimbra, Portugal.
Rui AlvesNephrology Department, Centro Hospitalar e Universitário de Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-3922-3618

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with a failed kidney allograft have steadily increase in recent years and returning to dialysis after graft loss is one of the most difficult transitions for chronic kidney disease patients and their assistant physicians. The management of these patients is complex and encompasses the treatment of chronic kidney disease complications, dialysis restart and access planning, immunosuppression withdrawal, graft nephrectomy, and evaluation for a potential retransplant. In recent years, several groups have focused on the management of the patient with a failing renal graft and expert recommendations are arising. A review of Pubmed, ScienceDirect and the Cochrane Library was performed focusing on the specific care of these patients, from the management of low clearance complications to concerns with a subsequent kidney transplant. Conclusion: There is a growing interest in the failing renal graft and new approaches to improve these patients' outcomes are being defined including specific multidisciplinary programs, individualized immunosuppression withdrawal schemes, and strategies to prevent HLA sensitization and increase retransplant rates.

Indexed as

chronic kidney diseasegraft intolerance syndromeimmunosuppressionkidney graft failurewithdrawal

Identifiers

PMID36294429
PMCPMC9605319

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.