Evidence map›Paper›PMID 36295756›Full record

ArticleMembranes2022

Possible Role of Bent Structure of Methylated Lithocholic Acid on Artificial and Plasma Membranes.

Tomoyuki Iwasaki, Nobuyuki Endo, Yuta Nakayama, Toshiyuki Kamei, Toshinori Shimanouchi, Hidemi Nakamura, Keita Hayashi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tomoyuki IwasakiDivision of Medical Research Support of the Advanced Research Support Center, Ehime University, Shitsukawa, Toon 791-0295, Ehime, Japan.ORCID 0000-0001-7646-7879
Nobuyuki EndoDepartment of Chemical Engineering, National Institute of Technology, Nara College, 22 Yata-cho, Yamatokoriyama 639-1080, Nara, Japan.
Yuta NakayamaDepartment of Chemical Engineering, National Institute of Technology, Nara College, 22 Yata-cho, Yamatokoriyama 639-1080, Nara, Japan.
Toshiyuki KameiDepartment of Chemical Engineering, National Institute of Technology, Nara College, 22 Yata-cho, Yamatokoriyama 639-1080, Nara, Japan.ORCID 0000-0001-8435-3767
Toshinori ShimanouchiGraduate School of Environmental and Life Science, Okayama University, 3-1-1 Tsushimanaka, Okayama 700-8530, Okayama, Japan.
Hidemi NakamuraDepartment of Chemical Engineering, National Institute of Technology, Nara College, 22 Yata-cho, Yamatokoriyama 639-1080, Nara, Japan.
Keita HayashiDepartment of Chemical Engineering, National Institute of Technology, Nara College, 22 Yata-cho, Yamatokoriyama 639-1080, Nara, Japan.ORCID 0000-0002-3119-9732
National Institute of Technology, Nara College · JPEhime University · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bile acids form micelles that are essential for the absorption of dietary lipids. However, excessive bile acid micelles can disrupt the plasma membrane by removing phospholipids, resulting in cell death. We hypothesized that the bent geometrical structure of the steroid scaffold of bile acids decreases the lipid order (similar to unsaturated phospholipids with

Indexed as

lipid membranemembrane propertysteroid molecule

Identifiers

PMID36295756
PMCPMC9610195
OpenAlexW4306391224

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.