Evidence map›Paper›PMID 36295902›Full record

ReviewMetabolites2022

Effects of Probiotics and Gut Microbiota on Bone Metabolism in Chickens: A Review.

Pan Chen, Tingting Xu, Chaodong Zhang, Xishuai Tong, Aftab Shaukat, Yanfeng He, Kaili Liu, Shucheng Huang

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Exploring the interplay betweenThe veterinary quarterly · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. DietaryVeterinary sciences · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Pan ChenCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Tingting XuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Chaodong ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Xishuai TongInstitutes of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China)/College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0002-2507-4749
Aftab ShaukatNational Center for International Research on Animal Genetics, Breeding and Reproduction (NCIRAGBR), Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-1670-6916
Yanfeng HeCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Kaili LiuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.
Shucheng HuangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China.ORCID 0000-0003-3163-8616
Henan Agricultural University · CNHuazhong Agricultural University · CNYangzhou University · CN

Funding

China Postdoctoral Science Foundation 2020M672234Key Scientific Research Project of Henan Higher Education Institutions of China 21A230013National Natural Science Foundation of China 32202876Outstanding Talents of Henan Agricultural University 30500421
6 · The paper itself

Abstract

Broiler leg diseases are a common abnormal bone metabolism issue that leads to poor leg health in growing poultry. Bone metabolism is a complicated regulatory process controlled by genetic, nutritional, feeding management, environmental, or other influencing factors. The gut microbiota constitutes the largest micro-ecosystem in animals and is closely related to many metabolic disorders, including bone disease, by affecting the absorption of nutrients and the barrier function of the gastrointestinal tract and regulating the immune system and even the brain-gut-bone axis. Recently, probiotic-based dietary supplementation has emerged as an emerging strategy to improve bone health in chickens by regulating bone metabolism based on the gut-bone axis. This review aims to summarize the regulatory mechanisms of probiotics in the gut microbiota on bone metabolism and to provide new insights for the prevention and treatment of bone diseases in broiler chickens.

Indexed as

bone metabolismgut–bone axisgut microbiotaleg diseasepoultryprobiotics

Identifiers

PMID36295902
PMCPMC9612127
OpenAlexW4306938090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.