Evidence map›Paper›PMID 36297119›Full record

ArticleNutrients2022

Higher Potassium Intake and Lower Sodium Intake May Help in Reducing CVD Risk by Lowering Salt Sensitivity of Blood Pressure in the Han Chinese Population.

Yunyi Xie, Han Qi, Wenjuan Peng, Bingxiao Li, Fuyuan Wen, Fengxu Zhang, Ling Zhang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yunyi XieDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.ORCID 0000-0001-5182-1093
Han QiDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Wenjuan PengDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Bingxiao LiDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Fuyuan WenDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Fengxu ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Ling ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing 100069, China.ORCID 0000-0003-2468-864X
Capital Medical University · CN

Funding

National Key Research and Development Program of China 2016YFC0900600/2016YFC0900603National Natural Science Foundation of China 81973121&81373076
6 · The paper itself

Abstract

Sodium (Na) reduction with a parallel supplemental potassium (K) intake can prevent cardiovascular diseases (CVDs). The relationship of the urinary Na/K ratio and salt sensitivity of blood pressure (SSBP) with CVDs is not clearly explained. We assumed that the SSBP mediates the relationship between the Na/K ratio and CVDs. In total, 2055 subjects who had 24 h urine collected and SSBP determined were included in this study. CVD risk was estimated using the China-PAR equation. MediationMultivariate logistic regression was used to explore the associations between the Na/K ratio or SSBP with CVD risk. Mediation analysis using a logistic regression model was performed. Both the urinary Na/K ratio and SSBP were related to the estimated CVD risk (p < 0.05). The mediation analysis found that SSBP mediated approximately 12% of the association between Na/K ratio and CVD risk. Our findings indicate that higher K intake and lower Na intake may help in preventing CVD risk by reducing SSBP risk in individuals with normotension or stage-one hypertension.

Indexed as

Cardiovascular DiseasesHypertensionSodium, DietaryBlood PressureHumansPotassiumSodiumSodium ChlorideSodium Chloride, DietaryPotassiumSodiumSodium ChlorideSodium Chloride, DietarySodium, Dietarycardiovascular disease riskmediationsalt sensitivitytwenty-four-hour urinary sodium:potassium ratio

Identifiers

PMID36297119
PMCPMC9607620
OpenAlexW4307264571

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.