Evidence map›Paper›PMID 36297488›Full record

ArticlePharmaceutics2022

Characterization and Differential Cytotoxicity of Gramicidin Nanoparticles Combined with Cationic Polymer or Lipid Bilayer.

Yunys Pérez-Betancourt, Rachel Zaia, Marina Franchi Evangelista, Rodrigo Tadeu Ribeiro, Bruno Murillo Roncoleta, Beatriz Ideriha Mathiazzi, Ana Maria Carmona-Ribeiro

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Emerging Cationic Nanovaccines.Pharmaceutics · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yunys Pérez-BetancourtBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0003-4998-5173
Rachel ZaiaBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-6888-7432
Marina Franchi EvangelistaBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0003-1913-7720
Rodrigo Tadeu RibeiroBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-5099-4256
Bruno Murillo RoncoletaBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0002-1430-7543
Beatriz Ideriha MathiazziBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.
Ana Maria Carmona-RibeiroBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0001-8500-2707
Universidade de São Paulo · BR

Funding

National Council for Scientific and Technological Development 302352/2014-7National Council for Scientific and Technological Development 302758/2019-4São Paulo Research Foundation 2019/17685-2
6 · The paper itself

Abstract

Gramicidin (Gr) nanoparticles (NPs) and poly (diallyl dimethyl ammonium) chloride (PDDA) water dispersions were characterized and evaluated against Gram-positive and Gram-negative bacteria and fungus. Dynamic light scattering for sizing, zeta potential analysis, polydispersity, and colloidal stability over time characterized Gr NPs/PDDA dispersions, and plating and colony-forming units counting determined their microbicidal activity. Cell viabilities of

Indexed as

antimicrobial cationic lipidantimicrobial cationic polymerantimicrobial peptidebroad spectrum of antimicrobial activitydifferential Gr nanoparticles/PDDA cytotoxicitydynamic light scatteringnanoparticlesscanning electron microscopysupported cationic bilayer on silica with or without gramicidin

Identifiers

PMID36297488
PMCPMC9610547
OpenAlexW4297474533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.