Evidence map›Paper›PMID 36301720›Full record

ArticlePhysiological reports2022

Aortic waveform responses to insulin in late versus early chronotype with metabolic syndrome.

Mary-Margaret E Remchak, Emily M Heiston, Anna Ballantyne, Brielle L Dotson, Steven K Malin

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Circadian rhythms and gastrointestinal hormone-related appetite regulation.Current opinion in endocrinology, diabetes, and obesity · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mary-Margaret E RemchakRutgers University, New Brunswick, New Jersey, USA.
Emily M HeistonUniversity of Virginia, Charlottesville, Virginia, USA.
Anna BallantyneUniversity of Virginia, Charlottesville, Virginia, USA.
Brielle L DotsonUniversity of Virginia, Charlottesville, Virginia, USA.
Steven K MalinRutgers University, New Brunswick, New Jersey, USA.ORCID 0000-0002-7360-6711
Rutgers, The State University of New Jersey · USUniversity of Virginia · USVirginia Commonwealth University · US

Funding

Exercise Dose and Metformin for Vascular Health in Adults with Metabolic SyndromeR01HL130296 · NHLBI · UNIVERSITY OF VIRGINIA · PI MALIN, STEVEN K · 2017 to 2021
$3.7M
Multi-Disciplinary Training Program in Translational Cardiovascular ResearchT32HL149645 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Lauren Ashley Cowart, William Gregory Hundley · 2020 to 2026
$2.2M
NHLBI NIH HHS R01 HL130296NHLBI NIH HHS T32 HL149645NIH HHS RO1-HL130296
6 · The paper itself

Abstract

Late chronotype (LC) correlates with reduced metabolic insulin sensitivity and cardiovascular disease. It is unclear if insulin action on aortic waveforms and inflammation is altered in LC versus early chronotype (EC). Adults with metabolic syndrome (n = 39, MetS) were classified as either EC (Morning-Eveningness Questionnaire [MEQ] = 63.5 ± 1.2) or LC (MEQ = 45.5 ± 1.3). A 120 min euglycemic clamp (40 mU/m

Indexed as

HyperinsulinismInsulin ResistanceMetabolic SyndromeAdultBlood GlucoseGlucoseHumansInflammationInsulinTumor Necrosis Factor-alphaBlood GlucoseGlucoseInsulinTumor Necrosis Factor-alphaaugmentation indexinsulin resistanceobesity and inflammationpulse pressurepulse wave analysis

Identifiers

PMID36301720
PMCPMC9612142
OpenAlexW4307408014

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.