Evidence map›Paper›PMID 36303307›Full record

ArticleYonsei medical journal2022

Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data.

Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung-Kyu Suh, Yong-Gyu Park

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Article
  3. A Rare Coexistence of Turner Syndrome and Mycosis Fungoides: A Case ReportJournal of clinical research in pediatric endocrinology · 2026
    Article
  4. Article
  5. Lifelong medical challenges and immunogenetics of Turner syndrome.Clinical and experimental pediatrics · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Sung Eun KimDepartment of Pediatrics, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-1598-3500
Sang Hyun ParkDepartment of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-0612-2562
Kyungdo HanDepartment of Statistics and Actuarial Science, College of Natural Sciences, Soongsil University, Seoul, Korea. hkd917@naver.com.ORCID https://orcid.org/0000-0002-6096-1263
Won Kyoung ChoDepartment of Pediatrics, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. wendy626@catholic.ac.kr.ORCID https://orcid.org/0000-0003-0918-0565
Byung-Kyu SuhDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-1971-0232
Yong-Gyu ParkDepartment of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-8721-3230
Catholic University of Korea · KRSoongsil University · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KRThe Catholic University of Korea St. Vincent's Hospital · KR

Funding

Department of Pediatrics, College of Medicine, The Catholic University of KoreaSt. Vincent's Hospital, Research Institute of Medical Science Foundation SVHR-2020-14
6 · The paper itself

Abstract

purposeIn South Korea, investigations into Turner syndrome (TS) prevalence and TS-associated cancer and mortality are lacking. Accurate data were estimated from the National Health Insurance Service (NHIS) and the Rare Diseases Registry (RDR) records. MATERIALS AND

methodsData on patients with TS who were registered in the RDR between 2007 and 2017 were collected. To estimate TS-associated cancer and mortality risk, the data were compared with data of 1:3 age-matched controls.

resultsIn 2017, 2054 patients with TS were identified from a total population of 26186952 South Korean women; therefore, the prevalence was 7.84 per 100000 persons. TS prevalence across 10-year interval age groups were 11.82, 23.17, 18.37, 10.49, 4.09, and 0.38 for age under 10 years, teenagers, 20s, 30s, 40s, and older than 50, respectively (per 100000 persons). The cancer risk in patients with TS was higher than that of age-matched controls over 5.3 person-years [hazard ratio (HR)=1.82, 95% confidence interval (CI) 1.01-3.27,

conclusionNational prevalence of TS was suggested, and an increased risk of TS-associated thyroid cancer and mortality were observed in this study.

Indexed as

NeoplasmsTurner SyndromeAdolescentChildChild, PreschoolFemaleHumansNational Health ProgramsPrevalenceProportional Hazards ModelsRiskmortality riskPrevalencethyroid cancer riskturner syndrome

Identifiers

PMID36303307
PMCPMC9629904
OpenAlexW4307778805

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.