Evidence map›Paper›PMID 36304492›Full record

ArticleJournal of clinical and translational hepatology2022

Regional and National Trends of Adult Living Donor Liver Transplantation in the United States Over the Last Two Decades.

Saleh A Alqahtani, Ahmet Gurakar, Hani Tamim, Thomas D Schiano, Alan Bonder, Zachary Fricker, Marwan Kazimi, Devin E Eckhoff, Michael P Curry, Behnam Saberi

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical and translational hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Saleh A AlqahtaniJohns Hopkins University, Division of Gastroenterology and Hepatology, Baltimore, MD, USA.
Ahmet GurakarJohns Hopkins University, Division of Gastroenterology and Hepatology, Baltimore, MD, USA.
Hani TamimAmerican University of Beirut, Department of Internal Medicine, Beirut, Lebanon.
Thomas D SchianoIcahn School of Medicine at Mount Sinai, Division of Liver Diseases, New York, NY, USA.
Alan BonderBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Zachary FrickerBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Marwan KazimiBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Devin E EckhoffBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Michael P CurryBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Behnam SaberiBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-7157-5827
Beth Israel Deaconess Medical Center · USJohns Hopkins University · USUniversity Gastroenterology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Liver organ shortage remains a major health burden in the US, with more patients being waitlisted than the number of liver transplants (LTs) performed. This study investigated US national and regional trends in living donor LT (LDLT) and identified factors associated with recipient survival. Methods: We retrospectively analyzed LDLT recipients and donors from the United Network Organ Sharing/Organ Procurement Transplant Network database from 1998 until 2019 for clinical characteristics, demographic differences, and survival rate. National and regional trends in LDLT, recipient outcomes, and predictors of survival were analyzed. Results: Of the 223,571 candidates listed for an LT, 57.5% received an organ, of which only 4.2% were LDLTs. Annual adult LDLTs first peaked at 412 in 2001 but experienced a significant decline to 168 by 2009. LDLTs then gradually increased to 445 in 2019. Region 2 had the highest LDLT numbers ( Conclusions: Following a substantial decline after a peak in 2001, the number of adult LDLTs steadily increased from 2011 to 2019. However, LDLTs still constitute the minority of the transplant pool in the US. Life-saving policies to increase the use of LDLTs, particularly in regions of high organ demand, should be implemented.

Indexed as

Liver transplantationLiving donorOrgan demandSurvivalUNOS

Identifiers

PMID36304492
PMCPMC9547266
OpenAlexW4225503934

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.