Evidence map›Paper›PMID 36311429›Full record

ReviewFrontiers in chemistry2022

Research progress on the antiviral activities of natural products and their derivatives: Structure-activity relationships.

Yajing Guo, Anna Ma, Xinyan Wang, Chen Yang, Xi Chen, Gen Li, Feng Qiu

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Anti-Infective Activity ofAntibiotics (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yajing GuoSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Anna MaSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xinyan WangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Chen YangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Xi ChenSchool of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Gen LiSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Feng QiuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses spread rapidly and are well-adapted to changing environmental events. They can infect the human body readily and trigger fatal diseases. A limited number of drugs are available for specific viral diseases, which can lead to non-efficacy against viral variants and drug resistance, so drugs with broad-spectrum antiviral activity are lacking. In recent years, a steady stream of new viral diseases has emerged, which has prompted development of new antiviral drugs. Natural products could be employed to develop new antiviral drugs because of their innovative structures and broad antiviral activities. This review summarizes the progress of natural products in antiviral research and their bright performance in drug resistance issues over the past 2 decades. Moreover, it fully discusses the effect of different structural types of natural products on antiviral activity in terms of structure-activity relationships. This review could provide a foundation for the development of antiviral drugs.

Indexed as

antiviralderivatizationnatural productsresistancestructural-activity relationship

Identifiers

PMID36311429
PMCPMC9596788

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.