Evidence map›Paper›PMID 36313208›Full record

ReviewAmerican journal of clinical and experimental urology2022

Understanding the link between kidney stones and cancers of the upper urinary tract and bladder.

Meredith Mihalopoulos, Alan Yaghoubian, Shirin Razdan, Johnathan A Khusid, Reza Mehrazin, Ketan K Badani, John P Sfakianos, William M Atallah, Ashutosh K Tewari, Peter Wiklund and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in American journal of clinical and experimental urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Meredith MihalopoulosDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Alan YaghoubianDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Shirin RazdanDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Johnathan A KhusidDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Reza MehrazinDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Ketan K BadaniDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
John P SfakianosDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
William M AtallahDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Ashutosh K TewariDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Peter WiklundDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Mantu GuptaDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Natasha KyprianouDepartment of Urology, Icahn School of Medicine at Mount Sinai New York, NY 10029, USA.
Icahn School of Medicine at Mount Sinai · USTisch Hospital · US

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Treatment-Induced Phenotypic Reprogramming in Prostate CancerR01CA232574 · NCI · UNIVERSITY OF KENTUCKY · PI KYPRIANOU, NATASHA · 2019 to 2023
$2.2M
NCATS NIH HHS UL1 TR004419NCI NIH HHS R01 CA232574
6 · The paper itself

Abstract

Kidney stones are one of the most common renal pathologies. While emerging evidence has implicated a potential association between kidney stones and upper urinary tract cancers (including renal cancer), there is limited understanding as to the common underlying biological pathways functionally linking the etiology of kidney stone formation and the incidence, development, and progression of urinary tract cancers. From a clinical perspective, kidney stone disease can be a barrier to oncologic care due to renal obstruction. From the epidemiological perspective, risk factors associated with both conditions include smoking, alcohol consumption, diet, and gender. Herein, we review the association between renal calculi and malignancy of the upper urinary tract and discuss the current understanding of (a) potential shared mechanisms, and (b) the impact this has on shared therapeutic management of both conditions.

Indexed as

bladder cancerKidney stone formationmechanisms of pathogenesisrenal cancer

Identifiers

PMID36313208
PMCPMC9605942
OpenAlexW4307969977

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.