Evidence map›Paper›PMID 36314115›Full record

ArticleBiomaterials science2022

N-Cadherin adhesive ligation regulates mechanosensitive neural stem cell lineage commitment in 3D matrices.

Jieung Baek, Sanjay Kumar, David V Schaffer, Sung Gap Im

Open access · greenAbstract read
In one paragraph

Article in Biomaterials science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jieung BaekDept. of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID http://orcid.org/0000-0001-5542-5928
Sanjay KumarDept. of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID http://orcid.org/0000-0002-9996-4883
David V SchafferDept. of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Sung Gap ImDept. of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. sgim@kaist.ac.kr.ORCID http://orcid.org/0000-0002-2802-6398
University of California, Berkeley · USKorea Advanced Institute of Science and Technology · KRUniversity of California, San Francisco · US

Funding

Mechanisms of Neural Stem Cell MechanoregulationR01NS074831 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Sanjay Kumar, DAVID V SCHAFFER · 2012 to 2026
$5.9M
NINDS NIH HHS R01 NS074831
6 · The paper itself

Abstract

During differentiation, neural stem cells (NSCs) encounter diverse cues from their niche, including not only biophysical cues from the extracellular matrix (ECM) but also cell-cell communication. However, it is still poorly understood how these cues cumulatively regulate mechanosensitive NSC fate commitment, especially in 3D matrices that better mimic

Indexed as

CadherinsNeural Stem CellsAdhesivesCell DifferentiationHydrogelsNeurogenesisAdhesivesCadherinsHydrogels

Identifiers

PMID36314115
PMCPMC10195187
OpenAlexW4307773083

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.