Evidence map›Paper›PMID 36318154›Full record

ArticleJournal of medicinal chemistry2022

Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.

Venkatram R Atigadda, Mahendra P Kashyap, Zhengrong Yang, Debasish Chattopadhyay, Nathalia Melo, Rajesh Sinha, Olga V Belyaeva, Chu-Fang Chou, Pi-Ling Chang, Natalia Y Kedishvili and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Venkatram R AtigaddaORCID 0000-0003-0085-0403
Mahendra P Kashyap
Debasish Chattopadhyay
Nathalia Melo
Rajesh Sinha
Chu-Fang Chou
Pi-Ling Chang
Natalia Y Kedishvili
Clinton J Grubbs
Matthew B Renfrow
Donald D Muccio
Craig A Elmets
Mohammad Athar
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
UAB Rexinoids for Breast Cancer PreventionP50CA089019 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHOU, TONG · 2000 to 2011
$26.0M
UAB Research Center of Excellence in ArsenicalsU54ES030246 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2018 to 2022
$19.0M
RXR Rexinoids for Cancer ChemopreventionP01CA210946 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2017 to 2021
$7.3M
Short-Chain Dehydrogenases in Retinol/Sterol MetabolismR01AR076924 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KEDISHVILI, NATALIA Y · 2020 to 2024
$2.2M
Chemoprevention of environmental UVB-induced skin cancer in immunosuppressed miceR01ES026219 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2016 to 2020
$1.7M
NCI NIH HHS P01 CA210946NCI NIH HHS P30 CA013148NCI NIH HHS P50 CA089019NIAMS NIH HHS R01 AR076924NIEHS NIH HHS R01 ES026219NIEHS NIH HHS U54 ES030246
6 · The paper itself

Abstract

Compound

Indexed as

Skin NeoplasmsTetrahydronaphthalenesHumansInflammationLigandsRetinoid X ReceptorsTretinoinTriglyceridesLigandsRetinoid X ReceptorsTetrahydronaphthalenesTretinoinTriglycerides

Identifiers

PMID36318154
PMCPMC9942614
OpenAlexW4307840283

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.