Evidence map›Paper›PMID 36324871›Full record

ReviewMaterials advances2022

Nanoclays in medicine: a new frontier of an ancient medical practice.

Kalpana S Katti, Haneesh Jasuja, Sharad V Jaswandkar, Sibanwita Mohanty, Dinesh R Katti

Abstract readReview
In one paragraph

Review in Materials advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Materials today. Bio · 2024
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kalpana S KattiDepartment of Civil Construction and Environmental Engineering, North Dakota State University Fargo ND 58105 USA Kalpana.Katti@ndsu.edu 701-231-9504.ORCID https://orcid.org/0000-0002-1404-4018
Haneesh JasujaDepartment of Civil Construction and Environmental Engineering, North Dakota State University Fargo ND 58105 USA Kalpana.Katti@ndsu.edu 701-231-9504.
Sharad V JaswandkarDepartment of Civil Construction and Environmental Engineering, North Dakota State University Fargo ND 58105 USA Kalpana.Katti@ndsu.edu 701-231-9504.ORCID https://orcid.org/0000-0003-3959-0071
Sibanwita MohantyDepartment of Civil Construction and Environmental Engineering, North Dakota State University Fargo ND 58105 USA Kalpana.Katti@ndsu.edu 701-231-9504.
Dinesh R KattiDepartment of Civil Construction and Environmental Engineering, North Dakota State University Fargo ND 58105 USA Kalpana.Katti@ndsu.edu 701-231-9504.ORCID https://orcid.org/0000-0001-9866-2683

Funding

Tracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3M
NIGMS NIH HHS U54 GM128729
6 · The paper itself

Abstract

Clays have been used as early as 2500 BC in human civilization for medicinal purposes. The ease of availability, biocompatibility, and versatility of these unique charged 2D structures abundantly available in nature have enabled the extensive applications of clays in human history. Recent advances in the use of clays in nanostructures and as components of polymer clay nanocomposites have exponentially expanded the use of clays in medicine. This review covers the details of structures and biomedical applications of several common clays, including montmorillonite, LAPONITE®, kaolinite, and halloysite. Here we describe the applications of these clays in wound dressings as hemostatic agents in drug delivery of drugs for cancer and other diseases and tissue engineering. Also reviewed are recent experimental and modeling studies that elucidate the impact of clay structures on cellular processes and cell adhesion processes. Various mechanisms of clay-mediated bioactivity, including protein localization, modulation of cell adhesion, biomineralization, and the potential of clay nanoparticles to impact cell differentiation, are presented. We also review the current developments in understanding the impact of clays on cellular responses. This review also elucidates new emerging areas of use of nanoclays in osteogenesis and the development of

Identifiers

PMID36324871
PMCPMC9577303

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.