SynthesisCurrent cardiology reports2022
The Role of Depression on Treatment Adherence in Patients with Heart Failure-a Systematic Review of the Literature.
Synthesis in Current cardiology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Global prevalence and determinant factors of pain, depression, and anxiety among cancer patients: an umbrella review of systematic reviews and meta-analyses.BMC psychiatry · 2025Pooled it
- Psychosocial predictors of health behavior adherence in heart-failure patients with comorbid depression: a secondary analysis of the Hopeful Heart trial.BMC psychology · 2024Trial
- Prevalence and incidence of heart failure hospitalizations from 2005 to 2023 and determinants of optimal treatment implementation in clinical practice: A population-based study in Northern Italy.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Activation of the nucleus nuclear factor erythroid 2-related factor 2ghrelin/growth hormone secretagogue receptor 1a signaling by Yueju pill confers cardioprotective and antidepressant effects.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Drug Adherence After Hospitalisation for Heart Failure: What Have We Learned from a French Survey?Journal of clinical medicine · 2026Article
- Psychological distress and its influence on medication adherence among patients with co-morbid hypertension and diabetes: an explanatory sequential mixed-methods study.BMC public health · 2026Article
- Depressive Symptoms, Functional Status, and Cardiovascular Parameters in Patients with Major Depressive Disorder Undergoing Cardiac Rehabilitation While Treated with Vortioxetine: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Intelligent mobile health management for the risk of gastrointestinal bleeding in anticoagulated patients with cardiovascular disease.Revista da Escola de Enfermagem da U S P · 2026Observational
- Effectiveness of a comprehensive therapeutic milieu on quality of life and level of stress among patients with heart failure - An experimental study.Journal of education and health promotion · 2026Article
- Psychosocial determinants of anti-VEGF treatment adherence in AMD patients: optimization of one-stop intravitreal injection service model.Frontiers in medicine · 2026Article
- Recognizing anxiety and depression in cancer patients based on speech and facial expressions.Frontiers in psychiatry · 2026Article
- Adherence to guideline-directed medical treatments in heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Cardiovascular Pharmacotherapy.European journal of heart failure · 2025Review
- How hospital doctors respond to contextual factors revealed by older patients with heart failure in hospital interactions: an interaction-based study.BMC health services research · 2025Article
- Symptoms of Emotional Disorders and Their Co-Occurrence with Adherence Levels in Individuals Aged 55 and Older with Chronic Diseases.Journal of clinical medicine · 2025Article
- Effects of colchicine on depression scale scores of patients with chronic heart failure with reduced ejection fraction: A randomized clinical trial.Journal of cardiovascular and thoracic research · 2025Article
- Life-years lost associated with mental disorders in people with HIV: a cohort study in South Africa, Canada and the United States.Journal of the International AIDS Society · 2025Article
- Adherence to medical recommendations in high-risk pregnancy: dispositional and situational predictors with a focus on emotional reactivity.CNS spectrums · 2025Article
- Cognition, mood, self-care, and medication adherence in hospitalized patients with heart failure: a cross-sectional study.Scientific reports · 2025Article
- Medication non-adherence and its predictors among chronic heart failure patients in Northwest Amhara region.Scientific reports · 2025Article
- Frailty determinants in heart failure: Inflammatory markers, cognitive impairment and psychosocial interaction.ESC heart failure · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough poor medication adherence is considered an impacting risk factor for worsening heart failure (HF) outcomes, adherence rates in HF patients continue to be considerably low. To improve this condition, several studies investigated the impact of many determinants on medication adherence; however, few authors explored the role of depression on it. PURPOSE OF REVIEW: The purpose of this systematic review was to explore the association between depressive symptoms and medication adherence in HF patients. In particular, the research question was is depression a barrier to medication adherence in HF patients?
methodsA systematic review of quantitative analysis studies was undertaken. Six electronic databases were searched between the end of October and March 2022. Thirty-one trials were included, all of them assessed depression, adherence to medication, and their possible relationship.
resultsAs was intended, findings showed that the impact of a mild to moderate level of depression was significant on adherence to treatment in HF patients. However, many other risk factors emerged, like family support and health practices (es. low sodium diet).
conclusionThe detection of depression in the setting of HF should be crucial to HF patients' physical health and quality of life. Future research should take depression into account, exploring this area through self-report and qualitative interview as well.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.