Evidence map›Paper›PMID 36333689›Full record

ArticleBMC women's health2022

Pathways to ovarian cancer diagnosis: a qualitative study.

Katherine A Lawson-Michod, Melissa H Watt, Laurie Grieshober, Sarah E Green, Lea Karabegovic, Samantha Derzon, Makelle Owens, Rachel D McCarty, Jennifer A Doherty, Mollie E Barnard

Open access · goldAbstract read
In one paragraph

Article in BMC women's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. [Medical prior-guided TabMap deep learning model for ovarian cancer prediction and interpretability analysis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  2. Ovarian cancer presentation and management in sub-Saharan Africa: a scooping review protocal.Malawi medical journal : the journal of Medical Association of Malawi · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Katherine A Lawson-MichodHuntsman Cancer Institute, University of Utah, 2000 Cir of Hope Dr, Salt Lake City, UT, 84112, USA. Katherine.lawson-michod@hci.utah.edu.
Melissa H WattUniversity of Utah Intermountain Healthcare Department of Population Health Sciences, School of Medicine, University of Utah, 295 Chipeta Way, Salt Lake City, UT, 84108, USA.
Laurie GrieshoberHuntsman Cancer Institute, University of Utah, 2000 Cir of Hope Dr, Salt Lake City, UT, 84112, USA.
Sarah E GreenDepartment of Internal Medicine, School of Medicine, University of Utah, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
Lea KarabegovicDepartment of Internal Medicine, School of Medicine, University of Utah, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
Samantha DerzonDepartment of Internal Medicine, School of Medicine, University of Utah, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
Makelle OwensDepartment of Internal Medicine, School of Medicine, University of Utah, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
Rachel D McCartyHuntsman Cancer Institute, University of Utah, 2000 Cir of Hope Dr, Salt Lake City, UT, 84112, USA.
Jennifer A Doherty *Huntsman Cancer Institute, University of Utah, 2000 Cir of Hope Dr, Salt Lake City, UT, 84112, USA.
Mollie E Barnard *Huntsman Cancer Institute, University of Utah, 2000 Cir of Hope Dr, Salt Lake City, UT, 84112, USA.
Intermountain Healthcare · USHuntsman Cancer Institute · USDanbury Hospital · USSan Antonio Military Medical Center · USUniversity of Utah · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Max Loveless · 1986 to 2026
$72.6M
Inflammation and gynecologic cancer: the role of prostaglandins in ovarian cancerK00CA212222 · NCI · UNIVERSITY OF UTAH · PI BARNARD, MOLLIE ELYSE · 2018 to 2021
$415k
NCI NIH HHS K00 CA212222NCI NIH HHS P30 CA042014
6 · The paper itself

Abstract

backgroundOvarian cancer is often diagnosed at a late stage, when survival is poor. Qualitative narratives of patients' pathways to ovarian cancer diagnoses may identify opportunities for earlier cancer detection and, consequently, earlier stage at diagnosis.

methodsWe conducted semi-structured interviews of ovarian cancer patients and survivors (n = 14) and healthcare providers (n = 11) between 10/2019 and 10/2021. Interviews focused on the time leading up to an ovarian cancer diagnosis. Thematic analysis was conducted by two independent reviewers using a two-phase deductive and inductive coding approach. Deductive coding used a priori time intervals from the validated Model of Pathways to Treatment (MPT), including self-appraisal and management of symptoms, medical help-seeking, diagnosis, and pre-treatment. Inductive coding identified common themes within each stage of the MPT across patient and provider interviews.

resultsThe median age at ovarian cancer diagnosis was 61.5 years (range, 29-78 years), and the majority of participants (11/14) were diagnosed with advanced-stage disease. The median time from first symptom to initiation of treatment was 2.8 months (range, 19 days to 4.7 years). The appraisal and help-seeking intervals contributed the greatest delays in time-to-diagnosis for ovarian cancer. Nonspecific symptoms, perceptions of health and aging, avoidant coping strategies, symptom embarrassment, and concerns about potential judgment from providers prolonged the appraisal and help-seeking intervals. Patients and providers also emphasized access to care, including financial access, as critical to a timely diagnosis.

conclusionInterventions are urgently needed to reduce ovarian cancer morbidity and mortality. Population-level screening remains unlikely to improve ovarian cancer survival, but findings from our study suggest that developing interventions to improve self-appraisal of symptoms and reduce barriers to help-seeking could reduce time-to-diagnosis for ovarian cancer. Affordability of care and insurance may be particularly important for ovarian cancer patients diagnosed in the United States.

Indexed as

Early Detection of CancerOvarian NeoplasmsAdaptation, PsychologicalAdultAgedDiagnostic Self EvaluationFemaleHumansMiddle AgedQualitative ResearchAccess to healthcareDelayed diagnosisOvarian cancerPatient educationQualitative research

Identifiers

PMID36333689
PMCPMC9636716
OpenAlexW4308297349

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.