Evidence map›Paper›PMID 36337306›Full record

ReviewCureus2022

Classic and Current Opinions in Human Organ and Tissue Transplantation.

Angus N Oli, Adekunle Babajide Rowaiye, Samson Adedeji Adejumo, Francis Ifeanyi Anazodo, Rahnuma Ahmad, Susmita Sinha, Mainul Haque, Nihad Adnan

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Basics and Art of Immunosuppression in Liver Transplantation.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Angus N OliInfectious Disease, Nnamdi Azikiwe University, Agulu, NGA.
Adekunle Babajide RowaiyeBiotechnology, National Biotechnology Development Agency, Abuja, NGA.
Samson Adedeji AdejumoAllergy and Immunology, Federal University Oye Ekiti, Oye-Ekiti, NGA.
Francis Ifeanyi AnazodoInfectious Disease, Madonna University, Elele, NGA.
Rahnuma AhmadPhysiology, Medical College for Women and Hospital, Dhaka, BGD.
Susmita SinhaPhysiology, Khulna City Medical College and Hospital, Khulna, BGD.
Mainul HaquePharmacology and Therapeutics, National Defence University of Malaysia, Kuala Lumpur, MYS.
Nihad AdnanMicrobiology, Jahangirnagar University, Dhaka, BGD.
Madonna University · USFederal University Oye Ekiti · NGMedical College For Women and HospitalNational Defence University of Malaysia · MYNational Primary Health Care Development Agency · NGNnamdi Azikiwe University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graft tolerance is a pathophysiological condition heavily reliant on the dynamic interaction of the innate and adaptive immune systems. Genetic polymorphism determines immune responses to tissue/organ transplantation, and intricate humoral and cell-mediated mechanisms control these responses. In transplantation, the clinician's goal is to achieve a delicate equilibrium between the allogeneic immune response, undesired effects of the immunosuppressive drugs, and the existing morbidities that are potentially life-threatening. Transplant immunopathology involves sensitization, effector, and apoptosis phases which recruit and engages immunological cells like natural killer cells, lymphocytes, neutrophils, and monocytes. Similarly, these cells are involved in the transfer of normal or genetically engineered T cells. Advances in tissue transplantation would involve a profound knowledge of the molecular mechanisms that underpin the respective immunopathology involved and the design of precision medicines that are safe and effective.

Indexed as

allo-transplantbrief historygraftinggraft tolerancekidney transplantationregenerative medicinetissue engineeringtissue transplantationtypes of transplantationxeno-transplant

Identifiers

PMID36337306
PMCPMC9624478
OpenAlexW4308002760

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.