Evidence mapPaperPMID 36338286Full record

ArticleJournal of geriatric cardiology : JGC2022

Positive association between triglyceride glucose index and central systolic blood pressure among hypertensive adults.

Li Wang, Tian-Yu Cao, Jin-Qiao Li, Cong-Cong Ding, Jun-Pei Li, Hua-Bo Ying, Li-Shun Liu, Xiao Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric cardiology : JGC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Associations of the Triglyceride-Glucose Index and Body Fat Composition with Blood Pressure in Children and Adolescents.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Li WangDepartment of Nephrology, the Fourth Hospital of Harbin Medical University, Harbin, China.
Tian-Yu CaoBiological Anthropology, University of California Santa Barbara, California, USA.
Jin-Qiao LiDepartment of Urology Surgery, Graduate School of the Fourth Hospital of Harbin Medical University, Harbin, China.
Cong-Cong DingDepartment of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jun-Pei LiDepartment of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang, China.
Hua-Bo YingDepartment of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang, China.
Li-Shun LiuInstitute of Biomedicine, Anhui Medical University, Hefei, China.
Xiao HuangDepartment of Cardiology, the Second Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CNShenzhen Genoimmune Medical Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile studies have suggested the association between triglyceride-glucose (TyG) index, a reliable surrogate for insulin resistance and hypertension data are limited to the correlation of TyG and central blood pressure. This study aims to test the hypothesis that a higher TyG index is associated with elevated central systolic blood pressure (cSBP).

methodsA total of 9249 Chinese hypertensive adults from the H-type Hypertension and Stroke Prevention and Control Project were analyzed in this study. cSBP was measured noninvasively using an A-Pulse CASPro device. TyG index was calculated as ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2]. Smoothing curve and multivariate linear regression models [beta coefficient (β) with 95% CI] were applied to analyze the association between TyG index and cSBP. Subgroup analyses were conducted to explore potential modifications to such a correlation.

resultsThe overall mean TyG index is 8.8 ± 0.7, and the total mean cSBP is 131.3 ± 12.8 mmHg. TyG index was observed to be independently and positively associated with cSBP among the total population (β = 0.92, 95% CI: 0.53-1.31,

conclusionsTyG index is positively and independently associated with cSBP among hypertensive adults. Our study result suggests that TyG index might serve as an effective marker for vascular function.

Identifiers

PMID36338286
PMCPMC9618843
OpenAlexW4308555119

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.