ArticleJACC. Asia2022
Differences in Plaque Characteristics and Myocardial Mass: Implications for Physiological Significance.
Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04037163 (CCTA-FFR Registry for Development of Comprehensive Risk Prediction Model), which is not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
CCTA-FFR Registry for Development of Comprehensive Risk Prediction Model
Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Sex Differences in 5-Year Outcomes After Deferral of Revascularization Following Physiological Coronary Assessment.Circulation reports · 2024Article
- Practical Application of Coronary Physiologic Assessment: Asia-Pacific Expert Consensus Document: Part 2.JACC. Asia · 2023Review
- Sex Differences in Murray Law-Based Quantitative Flow Ratio Among Patients With Intermediate Coronary Lesions.Journal of the American Heart Association · 2023Article
- Multimodality OCT, IVUS and FFR evaluation of coronary intermediate grade lesions in women vs. men.Frontiers in cardiovascular medicine · 2023Article
- Coronary CT Angiography in the Cath Lab: Leveraging Artificial Intelligence to Plan and Guide Percutaneous Coronary Intervention.Interventional cardiology (London, England) · 2023Review
- Atherosclerosis With Immune Checkpoint Inhibitor Therapy: Evidence, Diagnosis, and Management:JACC. CardioOncology · 2022Review
- Reply: Myocardial Mass at Risk for Physiological Significance.JACC. Asia · 2022Article
- Myocardial Mass at Risk for Physiological Significance.JACC. Asia · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 12 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The mechanism of the fractional flow reserve (FFR) difference according to sex has not been clearly understood. Objectives: This study sought to evaluate sex differences in coronary stenosis, plaque characteristics, and left ventricular (LV) mass and their implications for physiological significance. Methods: This was a post hoc analysis of a pooled population of multicenter, international prospective cohorts. Patients (166 women and 489 men) underwent coronary computed tomography angiography (CCTA) within 90 days before invasive FFR measurements were included. The minimal lumen area, percent of plaque burden, whole vessel plaque volume by composition, high-risk plaque characteristics, and LV mass were analyzed from CCTA images. Results: Among 1,188 vessels analyzed, the FFR value was higher in women than that in men (0.85 ± 0.13 vs 0.82 ± 0.14; Conclusions: Higher FFR values for the same stenosis severity in women can be explained by fewer high-risk plaque characteristics and smaller myocardial mass in women than that in men. (CCTA-FFR Registry for Risk Prediction; NCT04037163).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.