Evidence map›Paper›PMID 36340478›Full record

ArticleWomen's health reports (New Rochelle, N.Y.)2022

Prospective Association of Circulating Adipokines with Cardiometabolic Risk Profile Among Women: The Rape Impact Cohort Evaluation Study.

Eileen Vuong, Nasheeta Peer, Esnat Chirwa, Shibe Mhlongo, Carl Lombard, Sian Hemmings, Andre Pascal Kengne, Naeemah Abrahams, Soraya Seedat

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Eileen VuongSouth African Research Chairs Initiative (SARChI), PTSD Program, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-5756-7687
Nasheeta PeerNon-Communicable Diseases Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Esnat ChirwaGender and Health Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Shibe MhlongoGender and Health Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Carl LombardBiostatistics Unit, South African Medical Research Council, Tygerberg, South Africa.
Sian HemmingsSouth African Research Chairs Initiative (SARChI), PTSD Program, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
Andre Pascal KengneNon-Communicable Diseases Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Naeemah AbrahamsGender and Health Research Unit, South African Medical Research Council, Tygerberg, South Africa.
Soraya SeedatSouth African Research Chairs Initiative (SARChI), PTSD Program, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
South African Medical Research Council · ZAStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sexual violence is associated with poor cardiometabolic outcomes, yet the etiopathogenic pathways remain unclear. Adipokines may contribute to pathways in the development of cardiometabolic disease (CMD), including in vulnerable populations. Further investigation of adipokines among sexually traumatized individuals may inform cardiometabolic screening. This study aimed to investigate the association between circulating adipokines, metabolic syndrome (MetS), and longitudinal change in MetS components (namely abdominal obesity, blood pressure, lipid profile, and glycemic status) over a 1-year period in a cohort of rape exposed (RE) and rape unexposed (RUE) females. Materials and Methods: Seven hundred seventy-eight RE and 617 RUE black South African women aged 18-40 years were recruited for the Rape Impact Cohort Evaluation study. Nonfasting blood samples were analyzed for cardiometabolic variables and adipokine levels using enzyme-linked immunosorbent assay. Serum adiponectin was measured in both RE and RUE and resistin, leptin, and leptin/adiponectin (L/A) ratio in RE only. Associations between baseline serum adipokines, MetS, and its components were assessed at baseline and follow-up using adjusted linear and logistic regressions. Results: In the RE group, adiponectin, leptin, and L/A ratio were significantly associated with MetS prevalence cross-sectionally (all Conclusions: Findings suggest that adipokines may have a potential role as biomarkers to identify RE individuals at high risk for CMD.

Indexed as

adipokinescardiometabolicrapeSouth Africa

Identifiers

PMID36340478
PMCPMC9629977
OpenAlexW4303488343

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.