Evidence map›Paper›PMID 36346572›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

The role of long non-coding RNA HCG18 in cancer.

Zhiqiang Wang, Rui Ran, Shunbai Zhang, Wenming Zhou, Jiayang Lv, Chunwei Ma, Haihong Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. LncRNAAsian journal of urology · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhiqiang WangLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Rui Ran *Lanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Shunbai ZhangLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Wenming ZhouLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Jiayang LvLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Chunwei MaLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China.
Haihong ZhangLanzhou University Second Hospital, 82 Cuiying Men, Lanzhou, 730000, People's Republic of China. 549990342@qq.com.ORCID http://orcid.org/0000-0003-0453-4184
Lanzhou University Second Hospital · CN

Funding

National Natural Science Foundation of China (No.31960175 )
6 · The paper itself

Abstract

The incidence of cancer is increasing worldwide and is becoming the most common cause of death. Identifying new biomarkers for cancer diagnosis and prognosis is important for developing cancer treatment strategies and reducing mortality. Long non-coding RNAs (lncRNAs) are non-coding, single-stranded RNAs that play an important role as oncogenes or tumor suppressors in the occurrence and development of human tumors. Abnormal expression of human leukocyte antigen complex group 18 (HCG18) is observed in many types of cancer, and its imbalance is closely related to cancer progression. HCG18 regulates cell proliferation, invasion, metastasis, and anti-apoptosis through a variety of mechanisms. Therefore, HCG18 is a potential tumor biomarker and therapeutic target. However, the therapeutic significance of HCG18 has not been well studied, and future research may develop new intervention strategies to combat cancer. In this study, we reviewed the biological function, mechanism, and potential clinical significance of HCG18 in various cancers to provide a reference for future research.

Indexed as

NeoplasmsRNA, Long NoncodingBiomarkers, TumorGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorRNA, Long NoncodingBiomarkerCancerceRNAHCG18lncRNAPrognosis

Identifiers

PMID36346572
OpenAlexW4308549921

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.