Evidence map›Paper›PMID 36347499›Full record

ArticleClinics and research in hepatology and gastroenterology2022

COVID-19-associated secondary sclerosing cholangitis - A case series of 4 patients.

Filipa Bordalo Ferreira, Margarida Mourato, Sofia Bragança, Joana Batista Paulo, Rita Sismeiro, André Pereira, Ana Nassauer Mónica, Luís Carvalho Lourenço, Mariana Cardoso

Abstract readCase Reports
In one paragraph

Article in Clinics and research in hepatology and gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. COVID-19-Related Cholangiopathy: Histological Findings.Diagnostics (Basel, Switzerland) · 2024
    Article
  2. COVID-19-associated secondary sclerosing cholangitis with liver transplantation.Virchows Archiv : an international journal of pathology · 2024
    Article
  3. Post-COVID-19 cholangiopathy: Systematic review.World journal of methodology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Filipa Bordalo FerreiraGastroenterology department, Hospital Professor Doutor Fernando Fonseca, IC 19, 2720-276 Amadora, Portugal. Electronic address: filipa.b.ferreira@hff.min-saude.pt.
Margarida MouratoInternal Medicine department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal, IC 19, 2720-276 Amadora, Portugal.
Sofia BragançaGastroenterology department, Hospital Professor Doutor Fernando Fonseca, IC 19, 2720-276 Amadora, Portugal.
Joana Batista PauloInternal Medicine department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal, IC 19, 2720-276 Amadora, Portugal.
Rita SismeiroInternal Medicine department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal, IC 19, 2720-276 Amadora, Portugal.
André PereiraPathology department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal, IC 19, 2720-276 Amadora, Portugal.
Ana Nassauer MónicaRadiology department, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal. IC 19, 2720-276 Amadora, Portugal.
Luís Carvalho LourençoGastroenterology department, Hospital Professor Doutor Fernando Fonseca, IC 19, 2720-276 Amadora, Portugal.
Mariana CardosoGastroenterology department, Hospital Professor Doutor Fernando Fonseca, IC 19, 2720-276 Amadora, Portugal.

Funding

Advancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132129
6 · The paper itself

Abstract

We report a case series of four patients diagnosed with COVID-19-associated secondary sclerosing cholangitis (SSC), a recently described rare late complication of severe COVID-19. Following prolonged stays in the intensive care unit, these patients developed marked sustained cholestasis and jaundice despite clinical improvement. Cholangiography showed beaded appearance of intra-hepatic bile ducts and bile casts were removed in one patient. None of the patients reached normalization of liver enzymes and at least one progressed to liver cirrhosis (follow-up time of 11 to 16 months). COVID-19-associated SSC has a dismal prognosis with rapid progression to advanced chronic liver disease.

Indexed as

Cholangitis, SclerosingCholestasisCOVID-19Bile Ducts, IntrahepaticCholangiographyHumansCase seriesCholangiopathyCOVID-19Secondary sclerosing cholangitis

Identifiers

PMID36347499
PMCPMC9636600

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.