Evidence map›Paper›PMID 36347939›Full record

ArticleScientific reports2022

Increased Ca

Junichi Ozawa, Seiko Ohno, Dario Melgari, Qi Wang, Megumi Fukuyama, Futoshi Toyoda, Takeru Makiyama, Masao Yoshinaga, Hiroshi Suzuki, Akihiko Saitoh and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Junichi OzawaDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Seiko OhnoDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Dario MelgariInstitute of Molecular and Translational Cardiology (IMTC), IRCCS Policlinico San Donato, 20097, San Donato Milanese, Milan, Italy.
Qi WangDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Megumi FukuyamaDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan.
Futoshi ToyodaDepartment of Physiology, Shiga University of Medical Science, Otsu, Japan.
Takeru MakiyamaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Masao YoshinagaDepartment of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
Hiroshi SuzukiDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Akihiko SaitohDepartment of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Tomohiko AiDepartment of Clinical Laboratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Minoru HorieDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga, 520-2192, Japan. horie@belle.shiga-med.ac.jp.
Shiga University of Medical Science · JPNiigata University · JPIndiana University – Purdue University Indianapolis · USIRCCS Policlinico San Donato · ITKagoshima Medical Center · JPKyoto University · JPNational Cerebral and Cardiovascular Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timothy syndrome (TS) is a rare pleiotropic disorder associated with long QT syndrome, syndactyly, dysmorphic features, and neurological symptoms. Several variants in exon 8 or 8a of CACNA1C, a gene encoding the α-subunit of voltage-gated Ca

Indexed as

Long QT SyndromeSyndactylyAutistic DisorderCalcium Channels, L-TypeFemaleHEK293 CellsHumansInfantMutationCACNA1C protein, humanCalcium Channels, L-Type

Identifiers

PMID36347939
PMCPMC9643354
OpenAlexW4308531330

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.