Evidence map›Paper›PMID 36348123›Full record

ArticleResults and problems in cell differentiation2022

Cellular Polarity Transmission to the Nucleus.

Paulina Nastały, Paolo Maiuri

Abstract read
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In one paragraph

Article in Results and problems in cell differentiation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paulina NastałyIFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. paulina.nastaly@gumed.edu.pl.
Paolo MaiuriIFOM ETS - The AIRC Institute of Molecular Oncology, Milan, Italy. paolo.maiuri@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polarity is an intrinsic and fundamental property of unicellular organisms and, as well, of single cells in multicellular ones. It can be defined as asymmetric cell organization that is self-reinforced and maintained by appropriate signaling. While cellular polarity is widely studied at the membrane and cytoplasmic level, if and how it is transmitted to the nucleus is still a matter of research and discussion. However, there is growing evidence of polarity transmission from the cell to the nucleus. In this chapter, we discuss recent reports on nuclear polarity and involvement of potential molecular players including emerin, nesprins, and nuclear F-actin which may play a significant role in establishment of this phenomenon.

Indexed as

Microfilament ProteinsNuclear EnvelopeCell NucleusCell PolarityNerve Tissue ProteinsMicrofilament ProteinsNerve Tissue ProteinsCell polarityEmerinNesprinNuclear F-actinNuclear polarityNucleus

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.