Evidence map›Paper›PMID 36348595›Full record

ArticleThe Indian journal of medical research

Do children with severe acute respiratory infection need cohorting & isolation before screening for COVID-19?

Rakesh Kumar, Ritesh Ranjan Sah, Anju Gupta, Karthi Nallasamy, Arnab Ghosh, Sanjay Verma

Abstract read
In one paragraph

Article in The Indian journal of medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rakesh KumarDepartment of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Ritesh Ranjan SahDepartment of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Anju GuptaDepartment of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Karthi NallasamyDepartment of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Arnab GhoshDepartment of Virology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Sanjay VermaDepartment of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective analysis was done to ascertain the SARS-CoV-2-positivity rate in children (0-12 yr) with severe acute respiratory infection (SARI) and compare it to those without SARI to determine the need for running a dedicated SARI isolation facility for paediatric COVID-19 care. The case records of 8780 children (0-12 yr) admitted and/or tested for SARS-CoV-2 between June 2020 and May 2021 at a tertiary care centre in north India were analyzed. The overall SARS-CoV-2 reverse transcription (RT)-PCR positivity rate was 3.0 per cent (262/8780). There were 1155 (13.15%) children with SARI. Fifty of these 1155 (4.3%) children with SARI, as against 212 of the 7625 (2.8%) children without SARI, tested positive for COVID-19. The absolute difference in the positivity rate among SARI and non-SARI groups was only 1.54 per cent which translates to cohorting and isolating 65 children with SARI to pick up one extra SARS-CoV-2-positive child (compared to those without SARI). The positive predictive value of SARI as a screening test was 4.3 per cent. Our findings suggest that isolation of children with SARI as a transmission-prevention strategy for COVID-19 may not be required. This is particularly relevant in resource-limited settings.

Indexed as

COVID-19ChildHumansMass ScreeningRetrospective StudiesSARS-CoV-2Tertiary Care CentersChildrenCOVID-19isolationRT-PCRSARISARS-CoV-2screening

Identifiers

PMID36348595
PMCPMC9807203

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.