Evidence map›Paper›PMID 36349705›Full record

ArticleJournal of cardiac surgery2022

Decreasing blood wastage during ex vivo lung perfusion recovery through utilization of thermal control technology.

Blaine Johnson, Jamie Bucio, Christopher Salerno, Valluvan Jeevanandam, Tae Song, Geoffrey Wool

Abstract read
In one paragraph

Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Blaine JohnsonPerfusion Services, UChicago Medicine, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0002-0502-9940
Jamie BucioDepartment of Surgery, Section of Cardiac Surgery, University of Chicago, Chicago, Illinois, USA.
Christopher SalernoDepartment of Surgery, Section of Cardiac Surgery, University of Chicago, Chicago, Illinois, USA.
Valluvan JeevanandamDepartment of Surgery, Section of Cardiac Surgery, University of Chicago, Chicago, Illinois, USA.
Tae SongDepartment of Surgery, Section of Cardiac Surgery, University of Chicago, Chicago, Illinois, USA.
Geoffrey WoolDepartment of Pathology, University of Chicago, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0002-3335-2905

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Organ Care System (OCS) is a revolutionary ex vivo organ perfusion technology that can potentially expand the organ retrieval range. The OCS Lung device uses packed red blood cells (pRBC) with a proprietary solution. We report the ability to reduce blood waste during this procedure by using a thermal packaging solution in conjunction with the OCS platform.

methodsWe retrospectively reviewed all OCS Lung recoveries performed by our recovery team, using pRBCfrom May 2019 to January 2021. Initially, units were stored using passive refrigeration with the Performance cooler at a temperature range of 1-6°C for 4 h. Subsequently, thermal control technology with the ProMed cooler was utilized to maintain the same temperature range for 72 h.

resultsTwenty-three recoveries were initiated with 63 pRBC. The Performance cooler was used for 8, while the ProMed cooler for 13. 37.5% of pRBC transported with the Performance cooler was used within the validated time range, while 25.0% were used beyond the validated time range based on clinical judgment. In addition, 37.5% of pRBC transported with the Performance cooler were returned to the institution after canceled recoveries with an estimated loss of $1800; the ProMed cooler had no wastage.

conclusionsThis study showed that using an advanced thermal packaging solution facilitates proper storage of pRBC and represents an advancement for extended donor lung preservation. The elimination of blood wastage in this initial study portends ongoing benefits for the limited blood supply and reduced cost.

Indexed as

Lung TransplantationOrgan PreservationExtracorporeal CirculationHumansLungPerfusionRetrospective Studiesblood usageblood wastageex vivo lung perfusionlung transplantationorgan care systemquality improvement

Identifiers

PMID36349705
PMCPMC10099649

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.