Evidence map›Paper›PMID 36350709›Full record

ReviewCancer biotherapy & radiopharmaceuticals2023

New Boron Delivery Agents.

Annette G Beck-Sickinger, Daniel P Becker, Oksana Chepurna, Bhaskar Das, Sebastian Flieger, Evamarie Hey-Hawkins, Narayan Hosmane, Satish S Jalisatgi, Hiroyuki Nakamura, Rameshwar Patil and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Cancer biotherapy & radiopharmaceuticals, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Uptakes of boronophenylalanine in theIBRO neuroscience reports · 2025
    Article
  3. Article
  4. A NovelPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Synthesis of New Promising BNCT Agents Based on Conjugates ofInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Single─Not Double─3D-Aromaticity in an OxidizedJournal of the American Chemical Society · 2023
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 4 countries.

Annette G Beck-SickingerFaculty of Life Sciences, Institute of Biochemistry, Leipzig University, Leipzig, Germany.
Daniel P BeckerDepartment of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, USA.
Oksana ChepurnaDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Bhaskar DasArnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York, USA.
Sebastian FliegerDepartment of Chemistry and Biochemistry, Loyola University Chicago, Chicago, Illinois, USA.
Evamarie Hey-HawkinsInstitute of Inorganic Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Leipzig, Germany.
Narayan HosmaneDepartment of Chemistry & Biochemistry, Northern Illinois University, DeKalb, Illinois, USA.
Satish S JalisatgiDepartment of Radiology, University of Missouri, Columbia, Missouri, USA.
Hiroyuki NakamuraLaboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Rameshwar PatilDepartment of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Maria da Graça H VicenteDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana, USA.ORCID 0000-0002-4429-7868
Clara ViñasInstitut de Ciencia de Materials de Barcelona, ICMAB-CSIC, Campus UAB, Bellaterra, Spain.
Cedars-Sinai Medical Center · USLeipzig University · DELoyola University Chicago · USInstitut de Ciència de Materials de Barcelona · ESLong Island University · USLouisiana State University · USNorthern Illinois University · USTokyo Institute of Technology · JPUniversity of Missouri · US

Funding

Maximizing Access to Research Careers at Louisiana State UniversityT34GM136452 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI VICENTE, MARIA DA GRACA HENRIQUES · 2020 to 2024
$1.6M
Targeted nano-boron based boron neutron capture therapy for glioma treatmentR21CA259911 · NCI · LOMA LINDA UNIVERSITY · PI PATIL, RAMESHWAR TUKARAM · 2022 to 2024
$439k
NCI NIH HHS R21 CA259911NIGMS NIH HHS T34 GM136452
6 · The paper itself

Abstract

This proceeding article compiles current research on the development of boron delivery drugs for boron neutron capture therapy that was presented and discussed at the National Cancer Institute (NCI) Workshop on Neutron Capture Therapy that took place on April 20-22, 2022. The most used boron sources are icosahedral boron clusters attached to peptides, proteins (such as albumin), porphyrin derivatives, dendrimers, polymers, and nanoparticles, or encapsulated into liposomes. These boron clusters and/or carriers can be labeled with contrast agents allowing for the use of imaging techniques, such as PET, SPECT, and fluorescence, that enable quantification of tumor-localized boron and their use as theranostic agents.

Indexed as

Boron Neutron Capture TherapyNeoplasmsBoronContrast MediaHumansLiposomesBoronContrast MediaLiposomesalbuminBNCTboron clusterliposomepeptideporphyrin

Identifiers

PMID36350709
PMCPMC10325817
OpenAlexW4308616743

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.