Evidence map›Paper›PMID 36352380›Full record

ArticleBMC complementary medicine and therapies2022

Classical music restored fertility status in rat model of premature ovarian failure.

Nahideh Nazdikbin Yamchi, Mohammad Mojtaba Alizadeh Ashrafi, Hamed Abbasi, Farhad Amjadi, Mohammad Hossein Geranmayeh, Reza Shirazi, Amin Tamadon, Reza Rahbarghazi, Mahdi Mahdipour

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Effects of music elements on mycophenolate glucuronidation in rat liver microsomes.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Nahideh Nazdikbin YamchiStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Mojtaba Alizadeh AshrafiFaculty of Design, Tabriz Islamic Art University, Tabriz, Iran.
Hamed AbbasiFaculty of Lyrical Literature, Islamic Azad University, Arak, Iran.
Farhad AmjadiStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Hossein GeranmayehNeurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Reza ShiraziDepartment of Anatomy, School of Medical Sciences, Medicine & Health, UNSW Sydney, Sydney, Australia.
Amin TamadonPercia Vista R&D Co., Shiraz, Iran.
Reza RahbarghaziStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahdi MahdipourStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Mahdi.Mahdipour@gmail.com.
Tabriz University of Medical Sciences · IRIslamic Azad University, Arak · IRTabriz Islamic Arts University · IRUNSW Sydney · AU

Funding

Tabriz University of Medical Sciences IR.TBZMED.VCR.REC.1398.361
6 · The paper itself

Abstract

backgroundThe restorative effect of classical music was assessed on the cyclophosphamide-induced animal model of premature ovarian failure (POF).

methodsMozart's piano classical music (K.448) was used for up to 4 and 8 weeks. Rats were exposed to music 6 h every day using a stereo system with a volume of 65-70 dB. Sera and ovarian tissue samples were collected for the evaluation of FSH, LH, and E

resultsHistopathological examination revealed a significant increase (p < 0.05) in the numbers of morphologically normal follicles at all the developmental stages in POF rats after music therapy compared to the POF group (p < 0.05). Music therapy decreased FSH and LH levels to near-to-normal levels conidied with elevation of E

conclusionResults showed that music can exert therapeutic effects on POF rats via the alteration of sex-related hormones.

Indexed as

MusicPrimary Ovarian InsufficiencyAnimalsFemaleFertilityFollicle Stimulating HormoneHumansPro-OpiomelanocortinRatsFollicle Stimulating HormonePro-OpiomelanocortinBrain activityMusic therapyOvarian rejuvenationPremature ovarian failureSex-related hormones

Identifiers

PMID36352380
PMCPMC9647984
OpenAlexW4308644805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.