Evidence map›Paper›PMID 36353136›Full record

ArticleFrontiers in neurology2022

Which is the most effective rescue treatment after the failure of mechanical thrombectomy for acute basilar artery occlusion?

Jun Luo, Deping Wu, Zhimin Li, Dongjing Xie, Jiacheng Huang, Jiaxing Song, Weidong Luo, Shuai Liu, Fengli Li, Wenjie Zi and 3 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Outcomes of stenting after failed basilar artery thrombectomy for acute stroke: a nationwide registry-based cohort study.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jun LuoDepartment of Neurology, Sichuan Mianyang 404 Hospital, Mianyang, China.
Deping WuDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Zhimin LiDepartment of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Dongjing XieDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Jiacheng HuangDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Jiaxing SongDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Weidong LuoDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Shuai LiuDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Fengli LiDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Wenjie ZiDepartment of Neurology, Xinqiao Hospital, The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Qiaojuan HuangDepartment of Cardiology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jiefeng LuoDepartment of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Deyan KongDepartment of Neurology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to evaluate the effectiveness and safety of rescue therapy, a therapy in which rescue devices such as balloon angioplasty, Apollo stent, Wingspan stent, Solitaire stent, or other self-expanding stents are used after the failure of mechanical thrombectomy (MT) and to determine the most effective rescue measure for acute basilar artery occlusion (BAO) after the failure of MT. Methods: For this study, we recruited patients from the BASILAR registry. All participants were divided into three groups: the recanalized with rescue therapy group, the recanalized without rescue therapy group, and the non-recanalized group. Clinical outcomes at 90 days and 1 year were compared. The association of rescue measures with favorable outcomes (modified Rankin Scale [mRS] score of 0-3) in patients achieving successful recanalization Results: Among the participants, recanalization failure was found in 112 patients and successful recanalization in 473 patients, with 218 patients receiving rescue therapy and 255 patients without rescue therapy. Of these, 111 (43.5%) patients in the recanalized without rescue therapy group, 65 (29.8%) patients in the recanalized with rescue therapy group, and nine (8.0%) patients in the non-recanalized group achieved favorable outcomes at 90 days. Both the recanalization with rescue therapy and the recanalization without rescue therapy groups were associated with favorable outcomes at 90 days and 1 year compared with the non-recanalized group. Moreover, in patients receiving rescue therapy, Wingspan stents, Apollo stents, and balloon angioplasty were associated with higher rates of favorable outcomes at 90 days and 1 year than Solitaire stents. Conclusion: Whether rescue therapy is administered or not, recanalization leads to favorable outcomes in patients with acute BAO. For acute BAO after MT failure, balloon angioplasty, Wingspan stenting, and Apollo stenting could be considered effective and safe rescue options but not Solitaire stenting.

Indexed as

basilar artery occlusionmechanical thrombectomyrecanalizationrescue therapystroke

Identifiers

PMID36353136
PMCPMC9637633

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.