Evidence map›Paper›PMID 36356015›Full record

ArticleToxins2022

Integrative Metabolomics and Proteomics Detected Hepatotoxicity in Mice Associated with Alkaloids from

Ke Zan, Wei Lei, Yaolei Li, Ying Wang, Lina Liu, Tiantian Zuo, Hongyu Jin, Shuangcheng Ma

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2026
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ke ZanNational Institutes for Food and Drug Control, Beijing 102629, China.
Wei LeiState Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Yaolei LiNational Institutes for Food and Drug Control, Beijing 102629, China.
Ying WangNational Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0000-0002-9659-3538
Lina LiuNational Institutes for Food and Drug Control, Beijing 102629, China.
Tiantian ZuoNational Institutes for Food and Drug Control, Beijing 102629, China.
Hongyu JinNational Institutes for Food and Drug Control, Beijing 102629, China.
Shuangcheng MaNational Institutes for Food and Drug Control, Beijing 102629, China.
National Institutes for Food and Drug Control · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The traditional Chinese herbal medicine

Indexed as

AlkaloidsChemical and Drug Induced Liver InjuryEupatoriumPyrrolizidine AlkaloidsAnimalsCholineFibrosisGlycerophospholipidsMetabolomicsMiceProteomicsAlkaloidsCholineGlycerophospholipidsPyrrolizidine AlkaloidsEupatorium fortunei Turcz.glycerophospholipid metabolismhepatotoxic mechanismspyrrolizidine alkaloids

Identifiers

PMID36356015
PMCPMC9698670
OpenAlexW4308392104

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.