Evidence map›Paper›PMID 36358913›Full record

ReviewBiomolecules2022

The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host's Complement System.

Sajad Rashidi, Reza Mansouri, Mohammad Ali-Hassanzadeh, Antonio Muro, Paul Nguewa, Raúl Manzano-Román

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Mechanisms by which Factor H protectsFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Sajad RashidiMolecular and Medicine Research Center, Khomein University of Medical Sciences, Khomein 38811, Iran.ORCID 0000-0002-4675-7274
Reza MansouriDepartment of Immunology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd 8915173143, Iran.
Mohammad Ali-HassanzadehDepartment of Immunology, School of Medicine, Jiroft University of Medical Sciences, Jiroft 7861615765, Iran.
Antonio MuroInfectious and Tropical Diseases Group (e-INTRO), Institute of Biomedical Research of Salamanca-Research Center for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, 37008 Salamanca, Spain.ORCID 0000-0003-0244-4740
Paul NguewaDepartment of Microbiology and Parasitology, ISTUN Institute of Tropical Health, IdiSNA (Navarra Institute for Health Research), University of Navarra, C/Irunlarrea 1, 31008 Pamplona, Spain.ORCID 0000-0002-2193-7316
Raúl Manzano-RománInfectious and Tropical Diseases Group (e-INTRO), Institute of Biomedical Research of Salamanca-Research Center for Tropical Diseases at the University of Salamanca (IBSAL-CIETUS), Faculty of Pharmacy, University of Salamanca, 37008 Salamanca, Spain.ORCID 0000-0002-5066-9496
Universidad de Salamanca · ESImam Khomeini Hospital · IRNavarre Institute of Health Research · ESShahid Sadoughi University of Medical Sciences and Health Services · IRUniversity of Jiroft · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites. Different pathogens including parasites have developed sophisticated strategies to defend themselves against complement killing. Some of these strategies include the employment, mimicking or inhibition of host's complement regulatory proteins, leading to complement evasion. Therefore, parasites are proven to use the manipulation of the complement system to assist them during infection and persistence. Herein, we attempt to study the interaction´s mechanisms of some prominent infectious protozoan parasites including

Indexed as

LeishmaniaParasitesPlasmodiumProtozoan InfectionsTrypanosomaAnimalsComplement System ProteinsComplement System Proteinscomplement evasion molecular interactionscomplement regulatory proteinscomplement systemprotozoan parasites

Identifiers

PMID36358913
PMCPMC9687244
OpenAlexW4307349042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.