Evidence map›Paper›PMID 36359190›Full record

ArticleBiomedicines2022

Associations of Warfarin Use with Risks of Ischemic Cerebrovascular Events and Major Bleeding in Patients with Hyperthyroidism-Related Atrial Fibrillation.

Sian-De Liu, Shwu-Jiuan Lin, Chin-Ying Ray, Fang-Tsyr Lin, Weei-Chin Lin, Li-Hsuan Wang

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sian-De LiuSchool of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Shwu-Jiuan LinSchool of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-6961-4890
Chin-Ying RayDepartment of Clinical Pharmacy, Chang Gung Memorial Hospital, Linkou, Taoyuan 333, Taiwan.
Fang-Tsyr LinSection of Hematology/Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Weei-Chin LinSection of Hematology/Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-6804-3205
Li-Hsuan WangSchool of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-8047-5310
Baylor College of Medicine · USChang Gung Memorial Hospital · TWTaipei Medical University · TWTaipei Medical University Hospital · TW

Funding

Taipei Medical University Hospital 111TMUH-MOST-07the New Taipei Municipal TuCheng Hospital (built and operated by the Chang Gung Medical Foundation) CFRPVVL0011
6 · The paper itself

Abstract

The use of oral anticoagulants for patients with new-onset hyperthyroidism-related atrial fibrillation (AF) is controversial. We aimed to evaluate the clinical benefits of warfarin therapy in this population. This retrospective cohort study used a data-cut of Taiwan Health and Welfare Database between 2000 and 2016. We compared warfarin users and nonusers among AF patients with hyperthyroidism. We used 1:2 propensity score matching to balance covariates and Cox regression model to calculate hazard ratios (HRs). The primary outcome was risk of ischemic stroke/transient ischemic attack (TIA), and the secondary outcome was major bleeding. After propensity score matching, we defined 90 and 168 hyperthyroidism-related AF patients with mean (SD) age of 59.9 ± 13.5 and 59.2 ± 14.6 in the warfarin-treated group and untreated group separately. The mean (SD) CHA2DS2-VASc scores for the two groups were 2.1 ± 1.6 and 1.8 ± 1.5, respectively. Patients with hyperthyroidism-related AF receiving warfarin had no significant risk of ischemic stroke/TIA (adjusted HR: 1.16, 95% confidence interval [CI]: 0.52-2.56,

Indexed as

atrial fibrillationhyperthyroidismischemic stroketransient ischemic attackwarfarin

Identifiers

PMID36359190
PMCPMC9687236
OpenAlexW4307122767

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.